2,2-Bisnaloxone
2,2-Bisnaloxone
CAS: 211738-08-8
Molecular Formula: C38H40N2O8
2,2-Bisnaloxone - Names and Identifiers
| Name | 2,2-Bisnaloxone |
| Synonyms | Naloxone-003 2,2-Bisnaloxone Naloxone BP impurity E Naloxone EP Impurity E VZXBORUALALXQH-OFGCZPNKSA-N |
| CAS | 211738-08-8 |
2,2-Bisnaloxone - Physico-chemical Properties
| Molecular Formula | C38H40N2O8 |
| Molar Mass | 652.73 |
| Density | 1.55±0.1 g/cm3(Predicted) |
| pKa | 8.14±0.40(Predicted) |
| Storage Condition | -20°C |
2,2-Bisnaloxone - Introduction
2,2-bisnaloxone (2,2-bisnaloxone) is a drug impurity, also known as dimeric naloxone. Its chemical formula is C40H44N4O12, the relative molecular mass is 756.8.
Regarding the properties of the compound, naloxone dimer is a crystalline solid with a white to yellow color. It is almost insoluble in water and has high solubility in organic solvents such as ethanol and chloroform. This substance is stable at room temperature and pressure, but may decompose under high temperature or light conditions.
Naloxone dimer is primarily used as an impurity in naloxone, a drug that blocks the effects of opioids. Naloxone is widely used as a drug for the treatment of poisoning or accidents caused by opioid overdose. However, naloxone dimer is an impure substance of naloxone, and its presence may reduce the potency and purity of the drug.
Regarding the preparation of naloxone dimer, it is not clear whether there is a specific synthesis method for reference. Because naloxone dimer mainly exists as an impurity of naloxone, it is necessary to take corresponding measures to control the formation of naloxone dimer when producing purified naloxone.
In terms of safety information, the toxicity data of naloxone dimer is limited, because it mainly exists as an impurity of naloxone, so its separate toxicity research is less. However, in the use of naloxone for the treatment of opioid drug intoxication, the presence of naloxone dimers may reduce the potency and efficacy of the drug. Therefore, when using naloxone, high-purity naloxone products should be selected as far as possible to ensure the maximum therapeutic effect.
Regarding the properties of the compound, naloxone dimer is a crystalline solid with a white to yellow color. It is almost insoluble in water and has high solubility in organic solvents such as ethanol and chloroform. This substance is stable at room temperature and pressure, but may decompose under high temperature or light conditions.
Naloxone dimer is primarily used as an impurity in naloxone, a drug that blocks the effects of opioids. Naloxone is widely used as a drug for the treatment of poisoning or accidents caused by opioid overdose. However, naloxone dimer is an impure substance of naloxone, and its presence may reduce the potency and purity of the drug.
Regarding the preparation of naloxone dimer, it is not clear whether there is a specific synthesis method for reference. Because naloxone dimer mainly exists as an impurity of naloxone, it is necessary to take corresponding measures to control the formation of naloxone dimer when producing purified naloxone.
In terms of safety information, the toxicity data of naloxone dimer is limited, because it mainly exists as an impurity of naloxone, so its separate toxicity research is less. However, in the use of naloxone for the treatment of opioid drug intoxication, the presence of naloxone dimers may reduce the potency and efficacy of the drug. Therefore, when using naloxone, high-purity naloxone products should be selected as far as possible to ensure the maximum therapeutic effect.
Last Update：2024-04-09 21:54:55
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Multiple SpecificationsSpot supply
Product Name: Naloxone Impurity 5（Naloxone EP Impurity E） Visit Supplier Webpage Request for quotationCAS: 211738-08-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 2,2-Bisnaloxone Visit Supplier Webpage Request for quotation
CAS: 211738-08-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 211738-08-8
Tel: 18301782025
Email: 3008007409@qq.com
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QQ: 3008007409
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