2,2-difluoro-2-(3-(trifluoromethyl)phenyl)ethan-1-ol - Names and Identifiers
2,2-difluoro-2-(3-(trifluoromethyl)phenyl)ethan-1-ol - Introduction
2,2-difluoro-2-(3-(trifluoromethyl)phenyl)ethan-1-ol is an organic compound with the chemical formula C10H8F5O. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless liquid
-Melting point:-1 ℃
-Boiling point: 96-98 ℃
-Density: 1.373g/cm³
-Solubility: Soluble in alcohol and ether solvents, insoluble in water
-chemical properties: the compound is a kind of organic alcohol with strong hybrid effect, which can carry out nucleophilic addition reaction, reduction reaction and so on.
Use:
- 2,2-difluoro-2-(3-(trifluoromethyl)phenyl)ethan-1-ol are commonly used as intermediates and reagents in organic synthesis.
-It can be used to synthesize organic compounds with biological activity, such as drugs, pesticides, etc.
Method:
- 2,2-difluoro-2-(3-(trifluoromethyl)phenyl)ethan-1-ol can be synthesized by the following steps: First, 3-(trifluoromethyl) benzaldehyde is reacted with magnesium fluoride hydride to obtain 2, 2-Difluoro-2-(3-(trifluoromethyl)phenyl) ethanol. Then, it is converted into 2,2-difluoro-2-(3-(trifluoromethyl)phenyl)ethan-1-ol by alcoholization under basic conditions.
Safety Information:
- 2,2-difluoro-2-(3-(trifluoromethyl)phenyl)ethan-1-ol irritant, avoid contact with skin and eyes.
-Use the compound with appropriate protective equipment, such as gloves, goggles, and protective clothing.
-Avoid inhaling its vapor during operation and ensure a well-ventilated working environment.
-The compound should be stored in a sealed container, away from fire and high temperature.
-When disposing of the waste of this compound, it is necessary to comply with the relevant local laws and regulations.
Last Update：2024-04-09 21:01:54