2,3,4,9-Tetrahydro-1H-carbazol-4-one
1,2,3,9-Tetrahydro-4H-Carbazol-4-One
CAS: 15128-52-6
Molecular Formula: C12H11NO
2,3,4,9-Tetrahydro-1H-carbazol-4-one - Names and Identifiers
| Name | 1,2,3,9-Tetrahydro-4H-Carbazol-4-One |
| Synonyms | RARECHEM AK MA K053 Ondansetron Impurity 1 Ondansetron Impurity 10 4-OXO-1,2,3,4-TETRAHYDROCARBAZOLE 4-Oxo-1,2,3,4-tetrahydrocarbazole 1,2,3,4-tetrahydro-4-0xocarbazole 1,2,3,9-Tetrahydro-4H-Carbazol-4-One 2,3,4,9-Tetrahydro-1H-carbazol-4-one 1,2,3,9-tetrhydro-4H-carbazole-4-one 1,2,3,9-Tetrahydro-4(H)-Carbazol-4-One Ondansetron Hydrochloride Dihydrate EP Impurity I |
| CAS | 15128-52-6 |
| EINECS | 604-791-9 |
| InChI | InChI=1/C12H11NO/c14-11-7-3-6-10-12(11)8-4-1-2-5-9(8)13-10/h1-2,4-5,13H,3,6-7H2 |
2,3,4,9-Tetrahydro-1H-carbazol-4-one - Physico-chemical Properties
| Molecular Formula | C12H11NO |
| Molar Mass | 185.22 |
| Density | 1.275±0.06 g/cm3(Predicted) |
| Melting Point | 224-226°C |
| Boling Point | 386.3±11.0 °C(Predicted) |
| Flash Point | 194.5°C |
| Solubility | DMSO (Slightly, Heated), Methanol (Slightly) |
| Vapor Presure | 3.59E-06mmHg at 25°C |
| Appearance | White powder |
| Color | Off-White to Beige |
| pKa | 15.84±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.689 |
| MDL | MFCD00173749 |
2,3,4,9-Tetrahydro-1H-carbazol-4-one - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
2,3,4,9-Tetrahydro-1H-carbazol-4-one - Introduction
1,2,3, (tetrahydrofurfuryl ketone), chemical formula C5H10O2, is a colorless liquid. Its main properties are as follows:
1. Solubility: 1,2,3, soluble in many organic solvents, such as ethanol, ether and Ketone solvents.
2. Melting point and boiling point: 1,2,3. The melting point is -45 ℃ and the boiling point is 174 ℃.
3. Stability: 1,2,3, stable, not easy to decompose, and can be stored for a long time.
1,2,3, the main uses are:
1. Industrial use: as an organic solvent, used in paints, coatings, adhesives, plastics and other industries.
2. Medical use: as a chemical intermediate, can be used in drug synthesis, pharmaceutical preparations and other fields.
The method for preparing 1,2,3, 5 is generally hydrogenated tetrahydrocarbazole. The specific preparation method is as follows:
Tetrahydrocarbazole is dissolved in an alcohol or ester solvent, and hydrogen is used as a reducing agent, and a hydrogenation reaction is carried out under the condition of adding an appropriate amount of catalyst (such as palladium or platinum). The reaction is usually carried out under normal pressure or reduced pressure, and the reaction temperature is between room temperature and 80°C.
Safety Information:
1,2,3, relatively safer, but still need to pay attention to the following matters:
1. Avoid contact with strong oxidants to prevent fire or explosion.
2. In the use of the process should pay attention to avoid contact with skin and eyes, such as accidental contact, should immediately rinse with water.
3. In the process of operation, should maintain a good ventilation environment, avoid inhalation of steam.
4. Storage should be away from fire and heat sources, and keep the container closed, avoid direct sunlight.
Note: The above content is for reference only. The specific use and safe operation need to be evaluated and implemented according to the specific situation.
1. Solubility: 1,2,3, soluble in many organic solvents, such as ethanol, ether and Ketone solvents.
2. Melting point and boiling point: 1,2,3. The melting point is -45 ℃ and the boiling point is 174 ℃.
3. Stability: 1,2,3, stable, not easy to decompose, and can be stored for a long time.
1,2,3, the main uses are:
1. Industrial use: as an organic solvent, used in paints, coatings, adhesives, plastics and other industries.
2. Medical use: as a chemical intermediate, can be used in drug synthesis, pharmaceutical preparations and other fields.
The method for preparing 1,2,3, 5 is generally hydrogenated tetrahydrocarbazole. The specific preparation method is as follows:
Tetrahydrocarbazole is dissolved in an alcohol or ester solvent, and hydrogen is used as a reducing agent, and a hydrogenation reaction is carried out under the condition of adding an appropriate amount of catalyst (such as palladium or platinum). The reaction is usually carried out under normal pressure or reduced pressure, and the reaction temperature is between room temperature and 80°C.
Safety Information:
1,2,3, relatively safer, but still need to pay attention to the following matters:
1. Avoid contact with strong oxidants to prevent fire or explosion.
2. In the use of the process should pay attention to avoid contact with skin and eyes, such as accidental contact, should immediately rinse with water.
3. In the process of operation, should maintain a good ventilation environment, avoid inhalation of steam.
4. Storage should be away from fire and heat sources, and keep the container closed, avoid direct sunlight.
Note: The above content is for reference only. The specific use and safe operation need to be evaluated and implemented according to the specific situation.
Last Update：2024-04-09 21:21:28
Supplier List
Spot supply
Product Name: 1,2,3,9-Tetrahydro-4H-Carbazol-4-One Request for quotationCAS: 15128-52-6
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: 1,2,3,9-Tetrahydro-4H-Carbazol-4-One Request for quotation
CAS: 15128-52-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 15128-52-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: 1,2,3,9-Tetrahydro-4(H)-Carbazol-4-One Visit Supplier Webpage Request for quotationCAS: 15128-52-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: 1,2,3,9-Tetrahydro-4H-Carbazol-4-One Request for quotationCAS: 15128-52-6
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: 1,2,3,9-Tetrahydro-4H-Carbazol-4-One Request for quotation
CAS: 15128-52-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 15128-52-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: 1,2,3,9-Tetrahydro-4(H)-Carbazol-4-One Visit Supplier Webpage Request for quotationCAS: 15128-52-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History