2,3,5,6-tetrafluoro-4-hydroxybenzoate

2,3,5,6-tetrafluoro-4-hydroxybenzoate - Names and Identifiers

Name	4-Hydroxy-2,3,5,6-tetrafluorobenzoic acid
Synonyms	AKOS BB-7901 ASISCHEM Z74677 TETRAFLUORO-4-HYDROXYBENZOIC ACID 2,3,5,6-tetrafluoro-4-hydroxybenzoate 4-HYDROXY-2,3,5,6-TETRAFLUOROBENZOIC ACID 4-Hydroxy-2,3,5,6-tetrafluorobenzoic acid 2,3,5,6-TETRAFLUORO-4-HYDROXYBENZOIC ACID 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid 2,3,5,6-TETRAFLUORO-4-HYDROXYBENZOIC ACID (TETRAFLUORO-4-HYDROXYBENZOIC ACID) 2,3,5,6-Tetrafluoro-4-HydroxybenzoicAcid(Tetrafluoro-4-HydroxybenzoicAcid)210.09
CAS	652-34-6
EINECS	629-970-9
InChI	InChI=1/C7H2F4O3/c8-2-1(7(13)14)3(9)5(11)6(12)4(2)10/h12H,(H,13,14)/p-1

2,3,5,6-tetrafluoro-4-hydroxybenzoate - Physico-chemical Properties

Molecular Formula	C7H2F4O3
Molar Mass	210.08
Density	1.792±0.06 g/cm3(Predicted)
Melting Point	148-150°C
Boling Point	274.3±40.0 °C(Predicted)
Flash Point	119.7°C
Water Solubility	Insoluble in water.
Vapor Presure	0.00265mmHg at 25°C
BRN	986011
pKa	2.03±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
MDL	MFCD00129952

2,3,5,6-tetrafluoro-4-hydroxybenzoate - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S39 - Wear eye / face protection. S60 - This material and its container must be disposed of as hazardous waste. S37 - Wear suitable gloves.
HS Code	29182900
Hazard Class	IRRITANT

2,3,5,6-tetrafluoro-4-hydroxybenzoate - Introduction

4-Hydroxy-2,3,5,6-tetrafluorobenzoic acid is an organic compound with the chemical formula C7H3F4O3.

Nature:
1. Appearance: Colorless crystalline solid.
2. melting point: about 162-165 ℃.
3. Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, dimethylformamide, etc.

Use:
4-Hydroxy-2,3,5, 6-Tetrafluorobenzoic acid has certain applications in the field of chemistry:
1. used as an important intermediate in organic synthesis, participate in the synthesis of fluorescent dyes, photosensitizers, etc.
2. can be used for the synthesis of biologically active molecules, such as drug precursors or target molecules.

Preparation Method:
4-Hydroxy-2,3,5,6-tetrafluorobenzoic acid can generally be synthesized by the following method:
1,3,5,6-tetrafluoroacetophenone is reacted with hydrazine hydrate under the alkaline condition of sodium carbonate to generate an imine intermediate, which is then acidified by hydrolysis to obtain the product. The reaction may require the use of appropriate solvents and catalysts.

Safety Information:
1. 4-Hydroxy-2,3,5, 6-Tetrafluorobenzoic acid is an organic compound, which may have certain toxicity and irritation. Protective equipment should be worn when contacting.
2. When using or handling the compound, it should be operated in a well-ventilated place to avoid inhalation or skin contact.
3. Waste shall be properly disposed according to local regulations.

Last Update：2024-04-09 15:17:59