2,3-BIS(CHLOROMETHYL)PYRIDINE - Names and Identifiers
2,3-BIS(CHLOROMETHYL)PYRIDINE - Physico-chemical Properties
Molecular Formula | C7H7Cl2N
|
Molar Mass | 176.04 |
Density | 1.275±0.06 g/cm3(Predicted) |
Boling Point | 264.5±30.0 °C(Predicted) |
Flash Point | 139.294°C |
Vapor Presure | 0.016mmHg at 25°C |
pKa | 2.94±0.22(Predicted) |
Refractive Index | 1.548 |
2,3-BIS(CHLOROMETHYL)PYRIDINE - Introduction
2,3-bis(chloromethyl)pyridine is an organic compound with the chemical formula C7H6Cl2N. It is a colorless to yellowish liquid with a pungent odor. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless to yellowish liquid
-Solubility: Soluble in most organic solvents such as ethanol, acetone and dimethylformamide
-Melting point:-40°C
-Boiling Point: 157-159°C
-Density: 1.298g/cm³
Use:
- 2,3-bis(chloromethyl)pyridine is mainly used as an intermediate in organic synthesis.
-It can be used in the preparation of antibacterial drugs, anti-cancer compounds and pesticides in drug synthesis.
-The compound can also be used as a catalyst precursor to participate in organic reactions such as etherification, amination and condensation reactions.
Preparation Method:
2,3-bis(chloromethyl)pyridine can be synthesized by the following methods:
1. pyridine and methyl chloride are reacted to obtain 2,3-bis(chloromethyl)pyridine, and the reaction conditions are normal temperature or heating.
Safety Information:
- 2,3-bis(chloromethyl)pyridine is an irritating compound that may cause irritation and burns on contact with skin and eyes. Therefore, appropriate personal protective equipment such as gloves and goggles should be worn during operation.
-It is also a flammable liquid to avoid static electricity accumulation and open flame contact. Keep away from fire and oxidizing agents when storing.
-If 2,3-bis(chloromethyl)pyridine is inhaled or ingested, seek medical help immediately.
-Appropriate safety procedures must be observed when storing and handling the compound.
Last Update:2024-04-09 20:48:19