2,3-DIFLUOROPHENYLALANINE - Names and Identifiers
Name | 2,3-Difluoro-DL-phenylalanine
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Synonyms | H-DL-Phe(2,3-F2)-OH 2,3-Difluorophenylalanine dl-2,3-Difluorophenylalanine DL-2,3-DIFLUOROPHENYLALANINE Phenylalanine, 2,3-difluoro- 2,3-DIFLUORO-DL-PHENYLALANINE 2,3-Difluoro-DL-phenylalanine 2-AMino-3-(2,3-difluorophenyl)propanoic acid 2-AMINO-3-(2,3-DIFLUORO-PHENYL)-PROPIONIC ACID 2-Amino-3-(2,3-difluorophenyl)propanoic acid, 2-Amino-3-(2,3-difluorophenyl)propionic acid
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CAS | 236754-62-4
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InChI | InChI=1/C9H9F2NO2/c10-6-3-1-2-5(8(6)11)4-7(12)9(13)14/h1-3,7H,4,12H2,(H,13,14) |
2,3-DIFLUOROPHENYLALANINE - Physico-chemical Properties
Molecular Formula | C9H9F2NO2
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Molar Mass | 201.17 |
Density | 1.379g/cm3 |
Boling Point | 306.9°C at 760 mmHg |
Flash Point | 139.4°C |
Vapor Presure | 0.000327mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.536 |
2,3-DIFLUOROPHENYLALANINE - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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Hazard Class | IRRITANT |
2,3-DIFLUOROPHENYLALANINE - Introduction
2,3-difluoro-DL-Phenylalanine is an organic compound with the chemical formula C9H10F2NO2. It is a derivative of phenylalanine, and there are fluorine atom substitutions at the 2 and 3 positions of the compound. Its properties are as follows:
1. Appearance: 2,3-difluoro-DL-Phenylalanine is white crystal or crystalline powder.
2. Solubility: It has low solubility in water, can be dissolved under acidic and neutral conditions, and has better solubility under alkaline conditions.
3. Thermal stability: It can be decomposed at high temperature.
2,3-difluoro-dl-phenylalanine has certain application value in the field of medicine and biochemistry, and is commonly used in the synthesis of biologically active organic compounds, drugs and diagnostic reagents. It is used in the pharmaceutical field as a synthetic enzyme inhibitor and as an internal standard in pharmaceutical analysis.
Its preparation is mainly carried out by synthetic chemical methods. A common preparation method is to use phenylalanine as a starting material and introduce fluorine atoms at the 2 and 3 positions by chemical reaction to obtain 2,3-difluoro-DL-phenylalanine.
Regarding safety information, 2,3-difluoro-DL-phenylalanine has low toxicity, but it is still necessary to pay attention to safe operation. During the operation, avoid inhaling dust or contact with the skin and eyes. If contact occurs, rinse immediately with plenty of water and seek medical attention. In addition, it should be stored in a dry, cool place, away from fire and oxidants.
Last Update:2024-04-09 20:52:54