2,3-Diamino-6-methylpyridine
5,6-Diamino-2-picoline
CAS: 33259-72-2
Molecular Formula: C6H9N3
2,3-Diamino-6-methylpyridine - Names and Identifiers
| Name | 5,6-Diamino-2-picoline |
| Synonyms | 5,6-Diamino-2-picoline 5,6-DIAMINO-2-PICOLINE, 6-Methyl-2,3-Pyridinediamine 6-Methyl-2,3-pyridinediamine 2,3-Diamino-6-methylpyridine 6-methylpyridine-2,3-diamine 2,3-diamino-6-methylpyridinium 2,3-PyridinediaMine, 6-Methyl- 6-methylpyridine-2,3-diamine 2HCl |
| CAS | 33259-72-2 |
| EINECS | 820-604-5 |
| InChI | InChI=1/C6H9N3/c1-4-2-3-5(7)6(8)9-4/h2-3H,7H2,1H3,(H2,8,9)/p+1 |
2,3-Diamino-6-methylpyridine - Physico-chemical Properties
| Molecular Formula | C6H9N3 |
| Molar Mass | 123.16 |
| Density | 1.190 |
| Melting Point | 69-70℃ |
| Boling Point | 295℃ |
| Flash Point | 157℃ |
| Vapor Presure | 0.00161mmHg at 25°C |
| pKa | 6.88±0.50(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.4690 (estimate) |
2,3-Diamino-6-methylpyridine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
2,3-Diamino-6-methylpyridine - Introduction
5,6-diamino-2-picoline, also known as dithiamine (dapsone), is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
5,6-diamino-2-picoline is a white crystalline solid that can be dissolved in acidic and neutral solvents, but is insoluble in water. It is stable at room temperature, but may decompose at high temperatures.
Use:
5,6-diamino-2-picoline is mainly used to treat skin diseases, such as pemphigus, acne and ichthyosis. It is also used to treat tuberculosis and malaria.
Preparation Method:
5,6-diamino-2-picoline is usually prepared by nitrosylation of aniline. First, aniline and sodium nitrite react under acidic conditions to produce nitroaniline. Then, nitrosoaniline undergoes a reduction reaction to form 5,6-diamino-2-picoline.
Safety Information:
5,6-diamino-2-picoline is a toxic substance and requires careful use. During use, safety procedures should be followed, including wearing protective gloves and glasses, and maintaining good ventilation. Avoid inhalation or contact with the substance. In case of accidental use or contact, seek medical help immediately.
Nature:
5,6-diamino-2-picoline is a white crystalline solid that can be dissolved in acidic and neutral solvents, but is insoluble in water. It is stable at room temperature, but may decompose at high temperatures.
Use:
5,6-diamino-2-picoline is mainly used to treat skin diseases, such as pemphigus, acne and ichthyosis. It is also used to treat tuberculosis and malaria.
Preparation Method:
5,6-diamino-2-picoline is usually prepared by nitrosylation of aniline. First, aniline and sodium nitrite react under acidic conditions to produce nitroaniline. Then, nitrosoaniline undergoes a reduction reaction to form 5,6-diamino-2-picoline.
Safety Information:
5,6-diamino-2-picoline is a toxic substance and requires careful use. During use, safety procedures should be followed, including wearing protective gloves and glasses, and maintaining good ventilation. Avoid inhalation or contact with the substance. In case of accidental use or contact, seek medical help immediately.
Last Update：2024-04-09 21:01:54
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CAS: 33259-72-2
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 33259-72-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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