2,3-Dimethylpiperazin
2,2-dimethylpiperazine
CAS: 84477-72-5
Molecular Formula: C6H14N2
2,3-Dimethylpiperazin - Names and Identifiers
| Name | 2,2-dimethylpiperazine |
| Synonyms | 2-dimethylpiperazine 2,3-Dimethylpiperazin 2,3-dimethylpiperazine 2,2-dimethylpiperazine 2,2-DIMETHYL-PIPERAZINE Piperazine, 2,2-dimethyl- piperazine, 2,3-dimethyl- cis-2,2-dimethylpiperazine 2,2-DiMethyl-piperazine 2HCl |
| CAS | 84477-72-5 |
| InChI | InChI=1/C6H14N2/c1-6(2)5-7-3-4-8-6/h7-8H,3-5H2,1-2H3 |
2,3-Dimethylpiperazin - Physico-chemical Properties
| Molecular Formula | C6H14N2 |
| Molar Mass | 114.19 |
| Density | 0.833±0.06 g/cm3(Predicted) |
| Boling Point | 155.2±8.0 °C(Predicted) |
| Flash Point | 38.899°C |
| Vapor Presure | 3.069mmHg at 25°C |
| pKa | 9.38±0.40(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.417 |
2,3-Dimethylpiperazin - Risk and Safety
| Risk Codes | R42 - May cause sensitization by inhalation R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | 61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN3077 |
2,3-Dimethylpiperazin - Introduction
2,2-dimethylpiperazine is an organic compound with a chemical formula of C6H14N2 and a molecular weight of 114.19g/mol. It is a colorless liquid with a special amine odor.
2,2-dimethylpiperazine is mainly used for the preparation of antihypertensive drugs piperazine and piperazine maleate, which are common pharmaceutical raw materials. In addition, it can also be used as a meta complex or catalyst in organic synthesis.
The method for preparing 2,2-dimethylpiperazine can be obtained by the reaction of azobis (Diisopropyl azodicarboxylate) with methylamine. First, 2,2-dimethylpiperazine isocyanate and diacetyldithiamidine are reacted in acetone to give 2,2-dimethylpiperazine. The synthesis method needs to pay attention to the operation should take the necessary safety measures, avoid contact with the skin and inhalation.
2,2-safety information of dimethylpiperazine: It is a flammable liquid, which may cause a fire when exposed to an open flame or high temperature. Its vapors can form flammable or explosive mixtures. During handling, use and storage, care should be taken to avoid contact with oxidants or strong acids to avoid dangerous reactions. Wear appropriate protective measures, such as chemical protective clothing, protective gloves and protective glasses. In the event of an accidental spill, appropriate removal measures should be taken promptly. When stored, it should be kept in a cool, well-ventilated place, and away from sources of fire or ignition.
In general, 2,2-dimethylpiperazine is an important organic synthesis intermediate, but it needs to be safe during use and storage.
2,2-dimethylpiperazine is mainly used for the preparation of antihypertensive drugs piperazine and piperazine maleate, which are common pharmaceutical raw materials. In addition, it can also be used as a meta complex or catalyst in organic synthesis.
The method for preparing 2,2-dimethylpiperazine can be obtained by the reaction of azobis (Diisopropyl azodicarboxylate) with methylamine. First, 2,2-dimethylpiperazine isocyanate and diacetyldithiamidine are reacted in acetone to give 2,2-dimethylpiperazine. The synthesis method needs to pay attention to the operation should take the necessary safety measures, avoid contact with the skin and inhalation.
2,2-safety information of dimethylpiperazine: It is a flammable liquid, which may cause a fire when exposed to an open flame or high temperature. Its vapors can form flammable or explosive mixtures. During handling, use and storage, care should be taken to avoid contact with oxidants or strong acids to avoid dangerous reactions. Wear appropriate protective measures, such as chemical protective clothing, protective gloves and protective glasses. In the event of an accidental spill, appropriate removal measures should be taken promptly. When stored, it should be kept in a cool, well-ventilated place, and away from sources of fire or ignition.
In general, 2,2-dimethylpiperazine is an important organic synthesis intermediate, but it needs to be safe during use and storage.
Last Update：2024-04-09 21:01:54
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