2,3-O-Isopropylidene-alpha,-D-ribofuranose - Names and Identifiers
Name | 2,3-O-Isopropylidene-alpha,beta-D-ribofuranose
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Synonyms | 2,3-O-Isopropylidene-D-ribose 2,3-O-ISOPROPYLIDENE-D-RIBOFURANOSE 2,3-O-Isopropylidene-D-ribofuranoside 2,3-O-ISOPROPYLIDENE-A,B-D-RIBOFURANOSE 2,3-O-(1-methylethylidene)pentofuranose 2,3Isopropylidene-alpha,~-D-ribofuranose 2,3-O-Isopropylidene-alpha,-D-ribofuranose 2,3-O-ISOPROPYLIDENE-ALPHA,SS-D-RIBOFURANOSE 2,3-O-ISOPROPYLIDENE-ALPHA,BETA-D-RIBOFURANOSE 2,3-O-Isopropylidene-alpha,beta-D-ribofuranose
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CAS | 13199-25-2
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EINECS | 000-000-0 |
InChI | InChI=1/C8H14O5/c1-8(2)12-5-4(3-9)11-7(10)6(5)13-8/h4-7,9-10H,3H2,1-2H3 |
2,3-O-Isopropylidene-alpha,-D-ribofuranose - Physico-chemical Properties
Molecular Formula | C8H14O5
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Molar Mass | 190.19 |
Density | 1.299±0.06 g/cm3(Predicted) |
Boling Point | 127-134 °C(Press: 0.07 Torr) |
Flash Point | 157.9°C |
Solubility | Soluble in acetone. |
Vapor Presure | 7.17E-06mmHg at 25°C |
Appearance | Solid |
Color | White to Pale Yellow Low-Melting |
pKa | 13.46±0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.485 |
MDL | MFCD01075718 |
2,3-O-Isopropylidene-alpha,-D-ribofuranose - Introduction
2,3-o-isopropylidene-a,b-D-ribofuranose, also known as ribose, is a carbohydrate compound exhibiting a cyclic structure. Its chemical formula is C5H10O5, which is composed of 5 carbon atoms, 10 hydrogen atoms and 5 oxygen atoms.
2,3-o-isopropylidene-a,b-D-ribofuranose is an important part of nucleic acid, including RNA (ribonucleic acid) and a part of covalently modified DNA (deoxyribonucleic acid). As a constituent unit of nucleic acids, ribose plays an important role in the transmission of genetic information and protein synthesis.
In addition, ribose is also widely used in biochemistry, pharmaceutical chemistry and food industry. In biochemistry, ribose can be used as a substrate for enzymes, participating in a variety of enzymatic reactions. In medicinal chemistry, ribose is often used to synthesize nucleoside drugs, such as antiviral drugs and anticancer drugs. In the food industry, ribose can be used as a sweetener, is widely used to make candy, chocolate and beverages.
The method for preparing ribose is generally synthesized by a ribosylation reaction. Specific steps include reacting with a substrate (e. g., glucose) and a catalyst (e. g., hydrochloric acid and an oxidizing agent) to form ribose. This process needs to be carried out under appropriate temperature and pH conditions, and factors such as reaction time and reactant ratios need to be controlled to ensure a high yield and purity of the synthesized product.
Regarding the safety information of ribose, it is generally safe under normal use conditions. Ribose is a natural product, in the appropriate amount, generally will not cause significant side effects. However, for certain populations, such as those with diabetes or metabolic-related disorders, it may be necessary to consult a doctor for advice to avoid excessive intake or unnecessary use. In addition, ribose should also be stored in dry, dark conditions to maintain its stability and quality.
Last Update:2024-04-09 21:54:55