2,3-Pyrazinedicarboxamide
2,3-Pyrazinedicarboxamide
CAS: 6164-78-9
Molecular Formula: C6H6N4O2
2,3-Pyrazinedicarboxamide - Names and Identifiers
| Name | 2,3-Pyrazinedicarboxamide |
| Synonyms | 2,3-Pyrazinedicaroxamide 2,3-Pyrazinedicarboxamide 2,3-PYRAZINEDICARBOXAMIDE pyrazine-2,3-dicarboxamide N-(4,7-dimethyl-2-oxo-1-benzopyran-6-yl)-2-(3-methylphenoxy)acetamide |
| CAS | 6164-78-9 |
| EINECS | 228-197-0 |
| InChI | InChI=1/C20H19NO4/c1-12-5-4-6-15(7-12)24-11-19(22)21-17-10-16-13(2)9-20(23)25-18(16)8-14(17)3/h4-10H,11H2,1-3H3,(H,21,22) |
2,3-Pyrazinedicarboxamide - Physico-chemical Properties
| Molecular Formula | C6H6N4O2 |
| Molar Mass | 166.14 |
| Density | 1.4434 (rough estimate) |
| Melting Point | 248 °C (dec.) (lit.) |
| Boling Point | 294.33°C (rough estimate) |
| Flash Point | 302.8°C |
| Vapor Presure | 2.55E-13mmHg at 25°C |
| pKa | 13.23±0.50(Predicted) |
| Refractive Index | 1.6700 (estimate) |
2,3-Pyrazinedicarboxamide - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
2,3-Pyrazinedicarboxamide - Introduction
2,3-Pyrazinedicarboxamide(2,3-Pyrazinedicarboxamide) is an organic compound with the chemical formula C6H6N4O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2,3-Pyrazinedicarboxamide is a white crystalline solid.
-Melting point: Its melting point range is 170-174°C.
-Solubility: 2,3-Pyrazinedicarboxamide has low solubility in water, but it is easier to dissolve in organic solvents.
Use:
- 2,3-Pyrazinedicarboxamide can be used as an intermediate in organic synthesis and can be used to synthesize other compounds, such as fluorescent dyes and pharmaceuticals.
-It can also be used as a dye labeling agent for deoxyribonucleic acid (DNA).
- 2,3-Pyrazinedicarboxamide can also be used to prepare macrocyclic compounds containing a pyrazine skeleton.
Preparation Method:
2,3-Pyrazinedicarboxamide can be synthesized by the following steps:
1. Under alkaline conditions, pyrazine (pyrazine) reacts with chloroformic acid (chloroacetic acid) to generate 2,3-pyrazinedicarboxylic acid (2,3-pyrazinedicarboxylic acid).
2.2,3-pyrazinedicarboxylic acid is esterified by acid catalysis and reacted with methanol (methanol) to obtain 2,3-Pyrazinedicarboxamide.
Safety Information:
- 2,3-Pyrazinedicarboxamide has no obvious toxicity and irritation under normal use conditions.
-However, as a chemical substance, necessary safety measures should be taken, including wearing appropriate personal protective equipment to avoid inhalation, contact with skin and eating.
-Avoid contact with strong oxidants, strong acids and strong bases during use or storage.
-If ingestion or accidental exposure, seek medical attention immediately and bring information about the compound.
Nature:
-Appearance: 2,3-Pyrazinedicarboxamide is a white crystalline solid.
-Melting point: Its melting point range is 170-174°C.
-Solubility: 2,3-Pyrazinedicarboxamide has low solubility in water, but it is easier to dissolve in organic solvents.
Use:
- 2,3-Pyrazinedicarboxamide can be used as an intermediate in organic synthesis and can be used to synthesize other compounds, such as fluorescent dyes and pharmaceuticals.
-It can also be used as a dye labeling agent for deoxyribonucleic acid (DNA).
- 2,3-Pyrazinedicarboxamide can also be used to prepare macrocyclic compounds containing a pyrazine skeleton.
Preparation Method:
2,3-Pyrazinedicarboxamide can be synthesized by the following steps:
1. Under alkaline conditions, pyrazine (pyrazine) reacts with chloroformic acid (chloroacetic acid) to generate 2,3-pyrazinedicarboxylic acid (2,3-pyrazinedicarboxylic acid).
2.2,3-pyrazinedicarboxylic acid is esterified by acid catalysis and reacted with methanol (methanol) to obtain 2,3-Pyrazinedicarboxamide.
Safety Information:
- 2,3-Pyrazinedicarboxamide has no obvious toxicity and irritation under normal use conditions.
-However, as a chemical substance, necessary safety measures should be taken, including wearing appropriate personal protective equipment to avoid inhalation, contact with skin and eating.
-Avoid contact with strong oxidants, strong acids and strong bases during use or storage.
-If ingestion or accidental exposure, seek medical attention immediately and bring information about the compound.
Last Update：2024-04-09 02:00:47
