2,3-dihyro-4-benzofuranamine

2,3-dihyro-4-benzofuranamine - Names and Identifiers

Name	2,3-dihyro-4-benzofuranamine
Synonyms	2,3-dihyro-4-benzofuranamine 4-Amino-2,3-dihydrobenzofuran 2,3-dihydrobenzofuran-4-aMine 2,3-DIHYDRO-4-BENZOFURANAMINE 4-benzofuranamine, 2,3-dihydro- 2,3-Dihydro-1-benzofuran-4-amine 2,3-Dihydro-1-benzofuran-4-ylamine 5H,6H,7H,7aH-cyclopenta[b]pyran-5-aMine 2,3-dihydrobenzofuran-4-amine hydrochloride
CAS	61090-37-7
InChI	InChI=1/C8H9NO/c9-7-2-1-3-8-6(7)4-5-10-8/h1-3H,4-5,9H2

2,3-dihyro-4-benzofuranamine - Physico-chemical Properties

Molecular Formula	C8H9NO
Molar Mass	135.16
Density	1.208±0.06 g/cm3(Predicted)
Boling Point	268.5±29.0 °C(Predicted)
Flash Point	134.491°C
Vapor Presure	0.008mmHg at 25°C
pKa	3.94±0.20(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.627

2,3-dihyro-4-benzofuranamine - Introduction

2,3-dihyro-4-benzofuranamine is an organic compound with the chemical formula C8H9NO. The following is a brief description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 2,3-dihyro-4-benzofuranamine is a colorless to pale yellow crystal or powder.
-Melting point: approximately 125-128°C.
-Solubility: Soluble in alcohol, insoluble in water.

Use:
-Drug intermediate: 2,3-dihyro-4-benzofuranamine is an important drug intermediate that can be used to synthesize a series of biologically active compounds.
-Chemical reagent: It can also be used as a reducing agent and catalyst in organic synthesis.

Preparation Method:
The preparation method of 2,3-dihyro-4-benzofuranamine is more complicated. One commonly used method is to obtain it through the cycloaddition reaction of methylbenzofuran. The specific preparation route is cumbersome, involving multi-step reactions and multiple intermediate products. Therefore, in the laboratory, the preparation of this compound requires certain organic synthesis operation experience and skills.

Safety Information:
- 2,3-dihyro-4-benzofuranamine has limited toxicity data, but it may have some toxicity based on the toxicological properties of related similar compounds. Therefore, safe handling procedures for chemicals should be observed during handling and storage.
-Specific safety measures include wearing suitable protective glasses, gloves and laboratory coats. At the same time, it should be operated in a well-ventilated laboratory and avoid inhaling its vapor or dust.
-If exposed to this compound, immediately flush the affected area with plenty of water and seek medical attention.

Last Update：2024-04-09 21:11:58