Molecular Formula | C7H7Br2N |
Molar Mass | 264.95 |
Density | 1.8413 (rough estimate) |
Melting Point | 44-49 °C |
Boling Point | 281.2±35.0 °C(Predicted) |
Flash Point | 123.9°C |
Vapor Presure | 0.00361mmHg at 25°C |
Appearance | grayish white to gray or light brown crystalline powder |
pKa | 1.69±0.10(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.6300 (estimate) |
Physical and Chemical Properties | Needle-like crystals. Melting point 50 °c. Soluble in ethanol. Can be volatile with steam. (Melting points of 39-41 °c have also been reported). |
Hazard Symbols | Xn - Harmful![]() |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
use | as a pharmaceutical intermediate, used to produce a new expectorant bromhexylamine hydrochloride (bisouping). |
production method | is obtained by bromination of o-toluidine. Chloroform and o-toluidine are added to the reaction pot, bromine is added dropwise at 20-25 ℃ for about 3-4h, and then heated and refluxed for 10h. Cooling, adjusting to the pH9-10 with ammonia water, standing in layers, collecting chloroform layer, recovering chloroform to obtain the finished product. |