2,4-Dichloro-8-methoxyquinazoline

2,4-Dichloro-8-methoxyquinazoline - Names and Identifiers

Name	2,4-Dichloro-8-methoxyquinazoline
Synonyms	2,4-Dichloro-8-methoxyquizoline 2,4-Dichloro-8-methoxyquinazoline 8-Methoxy-2,4-dichloroquinazoline Quinazoline, 2,4-dichloro-8-methoxy-
CAS	61948-60-5
InChI	InChI=1/C9H6Cl2N2O/c1-14-6-4-2-3-5-7(6)12-9(11)13-8(5)10/h2-4H,1H3

2,4-Dichloro-8-methoxyquinazoline - Physico-chemical Properties

Molecular Formula	C9H6Cl2N2O
Molar Mass	229.06
Density	1.450
Melting Point	157-159 °C
Boling Point	315.9±24.0 °C(Predicted)
Flash Point	144.865°C
Vapor Presure	0.001mmHg at 25°C
pKa	-0.84±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.638

2,4-Dichloro-8-methoxyquinazoline - Introduction

2, is an organic compound with the chemical formula C10H6Cl2N2O. It is a solid having a white crystalline powder and is soluble in organic solvents such as ethanol and dimethylformamide.

This compound has certain applications in the field of medicine. It can be used as an intermediate in the synthesis of various anti-tumor and anti-cancer drugs. These substituents play an important role in anti-tumor activity due to the methoxy and chlorine atoms in their structure. In addition, it is also used to study and develop new drug molecular structures.

There are many ways to prepare 2. The most common preparation method is the reaction of 2,4-dichloroquinazoline and methanol under acidic conditions, and the target product is purified by crystallization.

Regarding safety information, 2, is a chemical that requires appropriate safety measures when used. It may be irritating to the skin and eyes, so wear protective gloves and goggles when using it, and ensure a well-ventilated laboratory environment. In addition, it should be kept away from fire and high temperature, and stored in a dry place. If inhaled or in contact with skin or eyes, rinse immediately with plenty of water and seek medical attention. When using this compound, it should be handled in accordance with the relevant safety data and procedures.

Last Update：2024-04-09 21:04:16