2,4-Dimethoxyprimidine
2,4-Dimethoxypyrimidine
CAS: 3551-55-1
Molecular Formula: C6H8N2O2
2,4-Dimethoxyprimidine - Names and Identifiers
| Name | 2,4-Dimethoxypyrimidine |
| Synonyms | 2,4-dimethoxypyrimdine 2,4-Dimethoxyprimidine 2,4-Dimethoxypyrimidine 2,4-DIMETHOXYPYRIMIDINE Pyrimidine, 2,4-dimethoxy- (6CI,7CI,8CI,9CI) |
| CAS | 3551-55-1 |
| InChI | InChI=1/C6H8N2O2/c1-9-5-3-4-7-6(8-5)10-2/h3-4H,1-2H3 |
2,4-Dimethoxyprimidine - Physico-chemical Properties
| Molecular Formula | C6H8N2O2 |
| Molar Mass | 140.14 |
| Density | 1.1501 g/mL at 25 °C (lit.) |
| Melting Point | 17°C |
| Boling Point | 204-205 °C (lit.) |
| Flash Point | 198-200°F |
| Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| Vapor Presure | 0.0552mmHg at 25°C |
| Appearance | Oil |
| Color | Clear Colorless |
| pKa | 2.69±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.502(lit.) |
| MDL | MFCD00056028 |
| Physical and Chemical Properties | Colorless liquid. Boiling point 204-206 ℃. |
2,4-Dimethoxyprimidine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S23 - Do not breathe vapour. S24/25 - Avoid contact with skin and eyes. S36/37 - Wear suitable protective clothing and gloves. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | NA 1993 / PGIII |
| WGK Germany | 3 |
| HS Code | 29335990 |
2,4-Dimethoxyprimidine - Reference Information
| chemical properties | colorless liquid. Boiling point 204-206 ℃. |
| use | pharmaceutical intermediates. |
| production method | dichloropyrimidine is dissolved in anhydrous methanol, added dropwise to anhydrous sodium methoxide solution under stirring, refluxed for 45min, cooled, filtered to remove sodium chloride, the filtrate is evaporated to methanol at normal pressure, the residual liquid is dissolved with 30% sodium hydroxide, and extracted with ether. After the ether extract was washed with water and dehydrated with anhydrous sodium sulfate, the ether was evaporated and the fraction at 196-210 ℃ was collected to obtain 2,4-dimethoxypyrimidine with a yield of 83-88%. |
Last Update：2024-04-09 21:01:54
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View History
2,4-Dimethoxyprimidine
(TRIMETHYLSILYL)ETHYLENE
SODIUM PRASTERONR SULFATE
2-甲基-1-(4-甲硫基苯基)-2-吗啉-1-丙酮IHT-PI 907
TERT-BUTYL TRANS-4-HYDROXYCYCLOHEXYLCARBAMATE
二甲基二硫
2-甲基硫甲基-1-对三氟甲氧苯基丙-2-烯-1-酮
3-Cyanobenzoic acid
Ceftriaxone (sodium salt hydrate)
3-(Trifluoromethyl)benzonitrile
(TRIMETHYLSILYL)ETHYLENE
SODIUM PRASTERONR SULFATE
2-甲基-1-(4-甲硫基苯基)-2-吗啉-1-丙酮IHT-PI 907
TERT-BUTYL TRANS-4-HYDROXYCYCLOHEXYLCARBAMATE
二甲基二硫
2-甲基硫甲基-1-对三氟甲氧苯基丙-2-烯-1-酮
3-Cyanobenzoic acid
Ceftriaxone (sodium salt hydrate)
3-(Trifluoromethyl)benzonitrile