2,4-dichloro-1-iodobenzene
2,4-dichloro-1-iodobenzene
CAS: 29898-32-6
Molecular Formula: C6H3Cl2I
2,4-dichloro-1-iodobenzene - Names and Identifiers
| Name | 2,4-dichloro-1-iodobenzene |
| Synonyms | 2,4-DICHLOROIODOBENZENE 4-Iodo-m-dichlorobenzene 2,4-Dichlorophenyl iodide 2,4-dichloro-1-iodobenzene 1-Iodo-2,4-dichlorobenzene 1,3-DICHLORO-4-IODOBENZENE 2,4-DICHLORO-1-IODOBENZENE Benzene, 2,4-dichloro-1-iodo- |
| CAS | 29898-32-6 |
| EINECS | 249-938-4 |
| InChI | InChI=1/C6H3Cl2I/c7-4-1-2-6(9)5(8)3-4/h1-3H |
2,4-dichloro-1-iodobenzene - Physico-chemical Properties
| Molecular Formula | C6H3Cl2I |
| Molar Mass | 272.9 |
| Density | 2.01g/mLat 25°C(lit.) |
| Melting Point | 97-100°C |
| Boling Point | 262-263°C(lit.) |
| Flash Point | >230°F |
| Vapor Presure | 0.0189mmHg at 25°C |
| Specific Gravity | 2.010 |
| BRN | 2245130 |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Light Sensitive |
| Refractive Index | n20/D 1.647(lit.) |
| MDL | MFCD00001035 |
2,4-dichloro-1-iodobenzene - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
2,4-dichloro-1-iodobenzene - Introduction
2,4-Dichloroiodobenzene is an organic compound with the chemical formula C6H3Cl2I. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2,4-dichloro-iodobenzene is a colorless to pale yellow crystal or crystalline powder.
-Solubility: It is soluble in common organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Melting point: Its melting point range is 40-42 ° C.
-Stability: 2,4-dichloroiodobenzene is stable to air and water, but may react under strong acid and strong alkali conditions.
Use:
-Catalyst: 2,4-dichloro-iodobenzene can be used as a catalyst in organic synthesis reactions, such as aromatization reactions and alcohol dehydration reactions.
-Drug intermediate: It can also be used as an intermediate for synthetic drugs, such as the preparation of anti-tuberculosis drugs, anti-cancer drugs and hormone drugs.
Method:
The preparation of 2,4-dichloro-iodobenzene is generally obtained by the reaction of iodobenzene and cuprous chloride. First, iodobenzene is reacted with cuprous chloride in an ether solvent to produce 2,4-dichlorobenzene, and then potassium iodide is added to the reaction system to give 2,4-dichloroiodobenzene.
Safety Information:
2,4-dichloro-iodobenzene should take appropriate protective measures during operation, such as wearing protective gloves and goggles. It may irritate the eyes, skin and respiratory system. Avoid contact with oxidizing agents during use and storage.
Nature:
-Appearance: 2,4-dichloro-iodobenzene is a colorless to pale yellow crystal or crystalline powder.
-Solubility: It is soluble in common organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Melting point: Its melting point range is 40-42 ° C.
-Stability: 2,4-dichloroiodobenzene is stable to air and water, but may react under strong acid and strong alkali conditions.
Use:
-Catalyst: 2,4-dichloro-iodobenzene can be used as a catalyst in organic synthesis reactions, such as aromatization reactions and alcohol dehydration reactions.
-Drug intermediate: It can also be used as an intermediate for synthetic drugs, such as the preparation of anti-tuberculosis drugs, anti-cancer drugs and hormone drugs.
Method:
The preparation of 2,4-dichloro-iodobenzene is generally obtained by the reaction of iodobenzene and cuprous chloride. First, iodobenzene is reacted with cuprous chloride in an ether solvent to produce 2,4-dichlorobenzene, and then potassium iodide is added to the reaction system to give 2,4-dichloroiodobenzene.
Safety Information:
2,4-dichloro-iodobenzene should take appropriate protective measures during operation, such as wearing protective gloves and goggles. It may irritate the eyes, skin and respiratory system. Avoid contact with oxidizing agents during use and storage.
Last Update：2024-04-09 21:01:54
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