2,5,6-Trifluoropyridine-3-carbonitrile

2,5,6-Trifluoropyridine-3-carbonitrile - Names and Identifiers

Name	2,5,6-trifluoropyridine-3-carbonitrile
Synonyms	2,5,6-Trifluoronicotinonitrile 2,5,6-trifluoro-3-cyanopyridine 3-Cyano-2,5,6-trifluoropyridine 2,5,6-trifluoropyridin-3-carbonitrile 2,5,6-Trifluoronicotinic acid nitrile 2,5,6-Trifluoro-3-pyridinecarbonitrile 2,5,6-trifluoropyridine-3-carbonitrile 2,5,6-Trifluoronicotinic aicid nitrile 2,5,6-Trifluoropyridine-3-carbonitrile 2,5,6-Trifluoronicotinic Aicid Nitrile 3-Pyridinecarbonitrile, 2,5,6-trifluoro-
CAS	870065-73-9
InChI	InChI=1/C6HF3N2/c7-4-1-3(2-10)5(8)11-6(4)9/h1H

2,5,6-Trifluoropyridine-3-carbonitrile - Physico-chemical Properties

Molecular Formula	C6HF3N2
Molar Mass	158.08
Density	1.47±0.1 g/cm3(Predicted)
Boling Point	205.6±35.0 °C(Predicted)
Flash Point	78.156°C
Vapor Presure	0.248mmHg at 25°C
pKa	-11.96±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.46

2,5,6-Trifluoropyridine-3-carbonitrile - Introduction

2,5, is an organic compound with the chemical formula C6H2F3N. It is a colorless to pale yellow solid that is soluble in organic solvents such as ethanol and methylene chloride.

2,5, has a wide range of uses in the field of medicine. It can be used as an intermediate for the synthesis of drugs, pesticides and agricultural chemicals. Its acetonitrile group can be used to introduce other functional groups to synthesize compounds with specific biological activities.

Preparation 2,5, is usually obtained by the reaction of trifluoroacetic acid and 3-cyanopyridine. The reaction is carried out at a low temperature and using an acidic catalyst such as boron trifluoride or aluminum trichloride. The product obtained by the reaction can be filtered and crystallized to obtain a higher purity of 2,5.

In terms of safety, 2,5, Ti needs to be handled with care because it is a toxic chemical. When in use, wear appropriate protective equipment such as gloves, safety glasses and laboratory coats, and ensure that the operation is carried out in a well-ventilated place. Store it in a sealed container, away from fire and oxidizing agents. If skin contact or inhalation occurs, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 15:18:00