2,5-Dichlorophenylhydrazine
2,5-Dichlorophenylhydrazine
CAS: 305-15-7
Molecular Formula: C6H6Cl2N2
2,5-Dichlorophenylhydrazine - Names and Identifiers
| Name | 2,5-Dichlorophenylhydrazine |
| Synonyms | 2,5-DICHLOROPHENYLHYRAZINE 2,5-Dichlorophenylhydrazine -2,5-DICHLOROPHENYLHYDRAZINE (2,5-dichlorophenyl)-hydrazin 1-(2,5-DICHLOROPHENYL)HYDRAZINE Hydrazine, (2,5-dichlorophenyl)- |
| CAS | 305-15-7 |
| EINECS | 206-163-6 |
| InChI | InChI=1/C6H6Cl2N2/c7-4-1-2-5(8)6(3-4)10-9/h1-3,10H,9H2 |
2,5-Dichlorophenylhydrazine - Physico-chemical Properties
| Molecular Formula | C6H6Cl2N2 |
| Molar Mass | 177.03 |
| Density | 1.475g/cm3 |
| Melting Point | 100-104℃ |
| Boling Point | 266.8°C at 760 mmHg |
| Flash Point | 115.1°C |
| Vapor Presure | 0.00848mmHg at 25°C |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.665 |
| MDL | MFCD00007576 |
2,5-Dichlorophenylhydrazine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
2,5-Dichlorophenylhydrazine - Introduction
2,5-dichlorophenylhydrazine (2,5-dichlorophenylhydrazine) is an organic compound with the chemical formula C6H6Cl2N2. It is a colorless to pale yellow crystal, soluble in organic solvents such as ethanol and ether.
2,5-dichlorophenylhydrazine is widely used in organic synthesis as an intermediate for the synthesis of other compounds. It can be used as a synthetic raw material for pesticides, dyes and drugs. In the field of medicine, it is also used for the preparation of anti-tumor and anti-infection drugs.
The preparation method of 2,5-dichlorophenylhydrazine is relatively simple, and it can usually be obtained by reacting 2,5-dichlorophenylboronic acid with carbamate in the presence of hydrochloric acid and chlorocarbaldehyde. In the reaction, the borate and formate undergo a condensation reaction to give 2,5-dichlorophenylhydrazine.
Regarding safety information, 2,5-dichlorophenylhydrazine has certain toxicity. It irritates the eyes and respiratory system and may cause damage to the skin and digestive system. Appropriate safety precautions, such as wearing protective gloves, goggles and protective clothing, should be taken during use and handling. Avoid inhaling its dust or vapor, and ensure that it is operated in a well-ventilated place. If the compound is ingested or inhaled, seek medical advice immediately.
2,5-dichlorophenylhydrazine is widely used in organic synthesis as an intermediate for the synthesis of other compounds. It can be used as a synthetic raw material for pesticides, dyes and drugs. In the field of medicine, it is also used for the preparation of anti-tumor and anti-infection drugs.
The preparation method of 2,5-dichlorophenylhydrazine is relatively simple, and it can usually be obtained by reacting 2,5-dichlorophenylboronic acid with carbamate in the presence of hydrochloric acid and chlorocarbaldehyde. In the reaction, the borate and formate undergo a condensation reaction to give 2,5-dichlorophenylhydrazine.
Regarding safety information, 2,5-dichlorophenylhydrazine has certain toxicity. It irritates the eyes and respiratory system and may cause damage to the skin and digestive system. Appropriate safety precautions, such as wearing protective gloves, goggles and protective clothing, should be taken during use and handling. Avoid inhaling its dust or vapor, and ensure that it is operated in a well-ventilated place. If the compound is ingested or inhaled, seek medical advice immediately.
Last Update：2024-04-09 20:02:46
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