2,5-Difluoro-4-Methylbenzonitrile

2,5-Difluoro-4-Methylbenzonitrile - Names and Identifiers

Name	2,5-Difluoro-4-methylbenzonitrile
Synonyms	2,5-Difluoro-4-methylbenzonitrle 2,5-Difluoro-4-methylbenzonitrile 2,5-Difluoro-4-Methylbenzonitrile Benzonitrile, 2,5-difluoro-4-methyl-
CAS	1003708-66-4

2,5-Difluoro-4-Methylbenzonitrile - Physico-chemical Properties

Molecular Formula	C8H5F2N
Molar Mass	153.13
Density	1.21
Boling Point	216℃
Flash Point	84℃
Storage Condition	Sealed in dry,Room Temperature

2,5-Difluoro-4-Methylbenzonitrile - Introduction

2,5-Difluoro-4-methylbenzonitrile is an organic compound with the chemical formula C8H5F2N. The following is a description of its nature, use, preparation and safety information:

Nature:
2,5-difluoro-4-methylbenzonitrile is a colorless to light yellow crystal or powdery solid with a special benzonitrile odor. It has a boiling point of 220-223°C and a density of 1.42g/cm³. This compound is soluble in some organic solvents, such as ketone, methylene chloride and ether.

Use:
2,5-difluoro-4-methylbenzonitrile is often used as an intermediate in organic synthesis reactions. It can be used in the synthesis of other organic compounds, such as cyano-substituted benzene ring derivatives. This compound can also be used for the synthesis of pharmaceuticals and the preparation of pesticides.

Preparation Method:
2,5-difluoro-4-methylbenzonitrile can be prepared by reacting fluorinated phthalic anhydride with magnesium cyanide. First, phthalic anhydride and magnesium cyanide react to produce magnesium cyanide, and then react with methyl compounds to obtain the product difluoro-4-methylbenzonitrile, and finally fluorination reaction to obtain the final product 2,5-difluoro-4-methylbenzonitrile.

Safety Information:
2,5-difluoro-4-methylbenzonitrile has low toxicity under general conditions. However, prolonged exposure or heavy exposure can pose a health hazard. Care should be taken to avoid inhalation, swallowing or contact with skin. Wear appropriate protective equipment such as gloves, glasses and protective clothing as necessary.

Last Update：2024-04-09 21:01:54