2,5-Dimethoxybenzylamine
2,5-Dimethoxybenzylamine
CAS: 3275-95-4
Molecular Formula: C9H13NO2
2,5-Dimethoxybenzylamine - Names and Identifiers
| Name | 2,5-Dimethoxybenzylamine |
| Synonyms | Zilain 2,5-Dimethoxybenzyla 2,5-Dimethoxybenzylamine 2,5-dimethoxy-benzylamin 2,5-dimethoxy-benzenemethanamin 2,5-DiMethoxybenzeneMethanaMine (2,5-dimethoxyphenyl)methanamine 1-AMinoMethyl-2,5-diMethoxybenzene 2-(AMinoMethyl)-1,4-diMethoxybenzene |
| CAS | 3275-95-4 |
| InChI | InChI=1/C9H13NO2/c1-11-8-3-4-9(12-2)7(5-8)6-10/h3-5H,6,10H2,1-2H3 |
2,5-Dimethoxybenzylamine - Physico-chemical Properties
| Molecular Formula | C9H13NO2 |
| Molar Mass | 167.21 |
| Density | 1.11 g/mL at 25 °C (lit.) |
| Boling Point | 95 °C/0.2 mmHg (lit.) |
| Flash Point | >230°F |
| Appearance | clear liquid |
| Color | Colorless to Light orange to Yellow |
| pKa | 9.12±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | n20/D 1.548(lit.) |
| Physical and Chemical Properties | Boiling Point: 88 - 90 |
2,5-Dimethoxybenzylamine - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2735 8/PG 3 |
| WGK Germany | 3 |
| RTECS | DP4430000 |
| HS Code | 29222990 |
| Hazard Class | IRRITANT |
| Packing Group | III |
2,5-Dimethoxybenzylamine - Introduction
2,5-dimethoxybenzamine is an organic compound with the chemical formula C9H13NO2. Its properties are as follows:
Appearance: Colorless to light yellow liquid or solid;
Melting point: 37-41 ℃;
Boiling point: 224-228 ℃;
Density: 1.074 g/mL;
Solubility: Soluble in common organic solvents, such as chloroform, ether and alcohols.
2,5-dimethoxybenzylamine is commonly used in pharmaceutical and organic synthesis. It is an important intermediate that can be used in the synthesis of biologically active molecules. It can be used as a raw material for anti-malarial and anti-cancer drugs in the medical field. In addition, it can also be used to synthesize other drugs, pesticides and dyes.
There are two main methods for the preparation of 2,5-dimethoxybenzylamine. One is the reaction of 2,5-dimethoxybenzaldehyde with ammonia, and under appropriate reaction conditions, the product can be obtained. The other is the reaction of 2,5-dimethoxybenzyl alcohol with bromoacetate to generate 2,5-dimethoxybenzyl bromoacetate, which is then reduced to generate 2,5-dimethoxybenzene amine.
It is important to note that the use of 2,5-dimethoxybenzylamine is subject to laboratory safety regulations. It is an irritant substance that may cause irritation to the eyes, skin and respiratory system. Wear appropriate personal protective equipment to avoid contact with skin and eyes during operation. At the same time, store it in a sealed container, away from fire and other flammable materials. The temperature and operating conditions should be strictly controlled during use to ensure safety.
Appearance: Colorless to light yellow liquid or solid;
Melting point: 37-41 ℃;
Boiling point: 224-228 ℃;
Density: 1.074 g/mL;
Solubility: Soluble in common organic solvents, such as chloroform, ether and alcohols.
2,5-dimethoxybenzylamine is commonly used in pharmaceutical and organic synthesis. It is an important intermediate that can be used in the synthesis of biologically active molecules. It can be used as a raw material for anti-malarial and anti-cancer drugs in the medical field. In addition, it can also be used to synthesize other drugs, pesticides and dyes.
There are two main methods for the preparation of 2,5-dimethoxybenzylamine. One is the reaction of 2,5-dimethoxybenzaldehyde with ammonia, and under appropriate reaction conditions, the product can be obtained. The other is the reaction of 2,5-dimethoxybenzyl alcohol with bromoacetate to generate 2,5-dimethoxybenzyl bromoacetate, which is then reduced to generate 2,5-dimethoxybenzene amine.
It is important to note that the use of 2,5-dimethoxybenzylamine is subject to laboratory safety regulations. It is an irritant substance that may cause irritation to the eyes, skin and respiratory system. Wear appropriate personal protective equipment to avoid contact with skin and eyes during operation. At the same time, store it in a sealed container, away from fire and other flammable materials. The temperature and operating conditions should be strictly controlled during use to ensure safety.
Last Update：2024-04-09 21:11:58
