2,5-dichloroisonicotinaldehyde

2,5-dichloroisonicotinaldehyde - Names and Identifiers

Name	2,5-DICHLORO-4-FORMYLPYRIDINE
Synonyms	2,5-DICHLORO-4-FORMY 2,5-DICHLORO-4-FORMYLPYRIDINE 2,5-dichloroisonicotinaldehyde 2,5-dichloropyridine-4-carbaldehyde 2,5-dichloro-4-pyridinecarboxaldehyde 2,5-DICHLOROPYRIDINE-4-CARBOXALDEHYDE 4-Pyridinecarboxaldehyde, 2,5-dichloro- tert-butyl (3S,4S)-3-amino-4-methoxy-1-pyrrolidinecarboxylate hydrochloride
CAS	102645-33-0
InChI	InChI=1/C6H3Cl2NO/c7-5-2-9-6(8)1-4(5)3-10/h1-3H

2,5-dichloroisonicotinaldehyde - Physico-chemical Properties

Molecular Formula	C6H3Cl2NO
Molar Mass	176
Density	1.488±0.06 g/cm3(Predicted)
Melting Point	73-74°
Boling Point	256.3±35.0 °C(Predicted)
Flash Point	108.8°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	0.0155mmHg at 25°C
Appearance	Solid
Color	White to Off-White
pKa	-3.62±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.608
MDL	MFCD06410679

2,5-dichloroisonicotinaldehyde - Risk and Safety

Hazard Class

IRRITANT

2,5-dichloroisonicotinaldehyde - Introduction

2,5-Dichloropyridine -4-aldehyde is an organic compound also known as dichloropyridine -4-aldehyde. The following is an introduction to its nature, use, preparation and safety information:

Nature:
2,5-dichloropyridine -4-aldehyde has a chemical formula of C7H3Cl2NO and a relative molecular mass of 179.01. It is a colorless to pale yellow solid with a pungent odor. It is practically insoluble in water at room temperature and soluble in organic solvents such as alcohols and ethers.

Use:
2,5-dichloropyridine -4-aldehyde is widely used in chemical industry. It is often used as an intermediate in organic synthesis and can be used to synthesize drugs, dyes, photosensitive materials and pesticides. It can also be used as an antioxidant for rubber and plastics, as well as a raw material for surfactants.

Preparation Method:
2,5-dichloropyridine -4-aldehyde preparation methods are mainly the following:
1. It is obtained by the reaction of 2,5-dichloropyridine and aldehyde or ketone under alkaline conditions;
2.2,5-dichloropyridine -4-acyl chloride is obtained by reacting 2,5-dichloropyridine with chlorine, and then reacts with water to generate 2,5-dichloropyridine -4-aldehyde.

Safety Information:
2,5-dichloropyridine -4-aldehyde is an organic substance, which should be safe during use and storage. It can cause irritation to the eyes, skin and respiratory system. Wear chemical protective glasses, protective gloves and protective masks when using it. Avoid inhaling its vapor during operation and maintain good ventilation conditions. In case of inadvertent contact, immediately flush the affected area with plenty of water and seek medical attention. At the same time, 2,5-dichloropyridine-4-aldehyde should be stored in a dry, cool place, away from fire and oxidizing agents.

Last Update：2024-04-09 21:11:58