2,6-dichloro-7-fluoro-7-deaza-9H-purine
2,4-Dichloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine
CAS: 1053228-29-7
Molecular Formula: C6H2Cl2FN3
2,6-dichloro-7-fluoro-7-deaza-9H-purine - Names and Identifiers
2,6-dichloro-7-fluoro-7-deaza-9H-purine - Physico-chemical Properties
| Molecular Formula | C6H2Cl2FN3 |
| Molar Mass | 206 |
| Density | 1.769±0.06 g/cm3(Predicted) |
| Melting Point | 234 °C(Solv: dichloromethane (75-09-2)) |
| pKa | 8.82±0.50(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD16249867 |
2,6-dichloro-7-fluoro-7-deaza-9H-purine - Introduction
[2,3-d]pyrimidine is an organic compound with the chemical formula C6H2Cl2FN3. The following is a description of its nature, use, preparation and safety information:
1. nature:
-Appearance: 2, [2,3-d]pyrimidine is a colorless solid.
-Melting point: Its melting point is about 167-173°C.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF).
2. use:
- 2, [2,3-d]pyrimidine can be used as pharmaceutical intermediates for the synthesis of biologically active compounds.
-It has potential anti-cancer activity in the pharmaceutical field, so it can be used in cancer research and drug development.
3. preparation method: The preparation of
- 2, [2,3-d]pyrimidine is usually done by a multi-step synthesis method.
-A common synthesis method uses pyrrolo [2,3-d] pyrimidine as the starting material and adds the corresponding fluorine and chlorine atoms through fluorination and chlorination reactions.
4. Safety Information:
- 2, [2,3-d] Note that pyrimidine is an organic compound, correct safe operating procedures should be followed.
-It may be irritating to the skin, eyes and respiratory tract, so direct contact should be avoided during handling.
-Wear appropriate personal protective equipment during operation, such as lab gloves, goggles, and respiratory protective equipment.
-Waste should be disposed of in accordance with local regulations to avoid environmental pollution.
Please note that when handling, preparing or using any chemical substance, it is important to follow the safety procedures and consult the detailed safety data form for the chemical substance.
1. nature:
-Appearance: 2, [2,3-d]pyrimidine is a colorless solid.
-Melting point: Its melting point is about 167-173°C.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF).
2. use:
- 2, [2,3-d]pyrimidine can be used as pharmaceutical intermediates for the synthesis of biologically active compounds.
-It has potential anti-cancer activity in the pharmaceutical field, so it can be used in cancer research and drug development.
3. preparation method: The preparation of
- 2, [2,3-d]pyrimidine is usually done by a multi-step synthesis method.
-A common synthesis method uses pyrrolo [2,3-d] pyrimidine as the starting material and adds the corresponding fluorine and chlorine atoms through fluorination and chlorination reactions.
4. Safety Information:
- 2, [2,3-d] Note that pyrimidine is an organic compound, correct safe operating procedures should be followed.
-It may be irritating to the skin, eyes and respiratory tract, so direct contact should be avoided during handling.
-Wear appropriate personal protective equipment during operation, such as lab gloves, goggles, and respiratory protective equipment.
-Waste should be disposed of in accordance with local regulations to avoid environmental pollution.
Please note that when handling, preparing or using any chemical substance, it is important to follow the safety procedures and consult the detailed safety data form for the chemical substance.
Last Update：2024-04-09 20:49:11
