2-氰基-6-氟苯基硼酸

2-氰基-6-氟苯基硼酸 - Names and Identifiers

Name	Boronic acid, (2-cyano-6-fluorophenyl)-
Synonyms	Boronic acid, (2-cyano-6-fluorophenyl)- Boronic acid, B-(2-cyano-6-fluorophenyl)- Boronic acid, (2-cyano-6-fluorophenyl)- (9CI)
CAS	656235-44-8

2-氰基-6-氟苯基硼酸 - Physico-chemical Properties

Molecular Formula	C7H5BFNO2
Molar Mass	164.93
Density	1.35±0.1 g/cm3(Predicted)
Boling Point	367.7±52.0 °C(Predicted)
pKa	7.77±0.58(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

2-氰基-6-氟苯基硼酸 - Introduction

Boronic acid, (2-cyano-6-fluorophenyl)-, chemical formula C7H5BFNO2, has the following properties:

1. Appearance: Boronic acid, (2-cyano-6-fluorophenyl)-is a white to light yellow crystalline solid.
2. Solubility: It has good solubility in most organic solvents, such as methanol, ethanol, dimethylformamide, etc.
3. chemical properties: it is mainly an aromatic boric acid derivatives, aromatic and acidic. It is a weak acid that can form stable complexes with ligands. In addition, it can also be esterified to prepare other functional compounds.
4. Thermal stability: It has good thermal stability and can exist stably at a certain temperature.

Boronic acid, (2-cyano-6-fluorophenyl)-has a wide range of uses, including but not limited to the following:

1. organic synthesis: it can be used as an important intermediate in organic synthesis, for the synthesis of pesticides, drugs, dyes and other complex organic compounds.
2. Coordination chemistry: Due to its acidic and aromatic properties, it can be used as a ligand to form stable complexes. These complexes have important applications in catalytic reactions, supramolecular chemistry and other fields.
3. medicinal chemistry: Boronic acid, (2-cyano-6-fluorophenyl)-and its derivatives play an important role in drug discovery and development, and can be used to design new drug molecular structures.
4. Material chemistry: It can be used in the fields of modified polymers, dyes and electronic materials.

the method for preparing Boronic acid, (2-cyano-6-fluorophenyl)-mainly includes the reaction preparation of aromatic borate ester with cyano group and fluorine group substitution or negative impact ionization through impact ionization. The specific preparation method needs to be selected according to actual needs and conditions.

Regarding safety information, Boronic acid, (2-cyano-6-fluorophenyl)-has low toxicity, the following aspects should be noted:
1. may be irritating to the skin, eyes and mucous membranes, when handling should wear protective equipment.
2. avoid inhaling its dust or gas. If a large amount of dust or gas is inhaled, immediately stay away from the site and seek medical attention.
3. Avoid contact with oxidants and acids during storage to avoid dangerous reactions.

In practical applications, in order to ensure the safe use of the compound, it is recommended to follow the relevant operating procedures and safe operating guidelines.

Last Update：2024-04-09 21:04:16