2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quizolin-6-yl)oxy)ethan-1-ol
OSI-420, Free Base (Desmethyl Erlotinib)
CAS: 183321-86-0
Molecular Formula: C21H21N3O4
2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quizolin-6-yl)oxy)ethan-1-ol - Names and Identifiers
2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quizolin-6-yl)oxy)ethan-1-ol - Physico-chemical Properties
| Molecular Formula | C21H21N3O4 |
| Molar Mass | 379.41 |
| Density | 1.30 |
| Melting Point | 140-142°C |
| Storage Condition | -20°C Freezer |
| In vivo study | Desmethyl Erlotinib exhibits t 1/2 of 11.96±2.01 h in a pharmacokinetic study in Wistar rats. |
2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quizolin-6-yl)oxy)ethan-1-ol - Introduction
OSI-420 Free Base is a compound with the chemical name 1-(4-amino-3-oxo-6-(4-(2-(6-(trifluoromethyl) aryl)) ethylamino) phenyl) hexahydro-2H-pyran-2-yl) ethanone. The following is an introduction to the nature, use, method and safety information of OSI-420 Free Base:
Nature:
-Appearance: White to light yellow solid.
-Melting point: About 110-116 ℃.
-Solubility: OSI-420 Free Base is soluble in organic solvents, such as ethanol, acetone and dichloromethane.
Use:
- OSI-420 Free Base is an anti-tumor drug used in cancer treatment research. It is a multi-targeted tyrosine kinase inhibitor and has anti-angiogenic and anti-tumor activities.
Preparation Method:
-The preparation of OSI-420 Free Base has not been publicly disclosed in the literature. In General, methods for preparing such compounds may involve organic synthesis and chemical reactions.
Safety Information:
- OSI420-Free Base is a laboratory synthetic drug, limited to research use.
-Standard laboratory safety practices and personal protective measures should be followed for the use and handling of OSI-420 Free Base.
-specific safety information, such as toxicity, corrosivity and environmental impact needs to be referred to the safety data form (SDS) provided by the chemical supplier.
Nature:
-Appearance: White to light yellow solid.
-Melting point: About 110-116 ℃.
-Solubility: OSI-420 Free Base is soluble in organic solvents, such as ethanol, acetone and dichloromethane.
Use:
- OSI-420 Free Base is an anti-tumor drug used in cancer treatment research. It is a multi-targeted tyrosine kinase inhibitor and has anti-angiogenic and anti-tumor activities.
Preparation Method:
-The preparation of OSI-420 Free Base has not been publicly disclosed in the literature. In General, methods for preparing such compounds may involve organic synthesis and chemical reactions.
Safety Information:
- OSI420-Free Base is a laboratory synthetic drug, limited to research use.
-Standard laboratory safety practices and personal protective measures should be followed for the use and handling of OSI-420 Free Base.
-specific safety information, such as toxicity, corrosivity and environmental impact needs to be referred to the safety data form (SDS) provided by the chemical supplier.
Last Update：2024-04-09 20:02:46
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Product Name: Erlotinib Impurity 167 Visit Supplier Webpage Request for quotationCAS: 183321-86-0
Tel: 0714-3999186
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Multiple Specifications
Product Name: OSI-420, Free Base (Desmethyl Erlotinib) Visit Supplier Webpage Request for quotationCAS: 183321-86-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Erlotinib Impurity 167 Visit Supplier Webpage Request for quotationCAS: 183321-86-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple Specifications
Product Name: OSI-420, Free Base (Desmethyl Erlotinib) Visit Supplier Webpage Request for quotationCAS: 183321-86-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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