2-(1,1-difluoro-2-hydroxyethyl)-6-fluorobenzonitrile - Names and Identifiers
2-(1,1-difluoro-2-hydroxyethyl)-6-fluorobenzonitrile - Introduction
2-(1,)-6-fluorobontril en is an organic compound with the chemical formula c9h53o and the structural formula C64 (cf2o)(CF3).
Nature:
2-(1,)-6-fluorobenzonite is a colorless or slightly yellow organic solid. It has high thermal stability and solubility, and can be dissolved in many organic solvents at room temperature, such as alcohol, ether, etc. It is stable in air, but may decompose at high temperatures.
Use:
2-(1,)-6-fluorobenzonite has a wide range of applications. It is often used as a pharmaceutical intermediate for the synthesis of a variety of drugs, such as anticancer drugs. In addition, it can also be used in the synthesis of aromatic compounds in organic synthesis reactions, such as cyanation reactions and hydroxylation reactions.
Method:
2-(1,)-6-fluorobenzonite can be synthesized by a variety of methods. A common method is by the reaction of terephthalic anhydride with difluoromethanesulfonyl fluoride to give 2-(1,-)-6-fluorobenzonite.
Safety Information:
2-(1,)-6-fluorobenzonitril has low toxicity and danger, but it is still necessary to pay attention to safe operation. Wear protective gloves, goggles and suitable protective clothing during handling. Avoid inhalation, ingestion or contact with skin and eyes. In case of inadvertent contact, immediately flush the affected area with plenty of water and seek medical help. When stored, should be away from fire and oxidant, stored in a cool, dry and well-ventilated place.
Last Update：2024-04-09 20:52:54