2-(1H-1,2,4-Triazol-1-ylmethyl)cycloheptanone
2-(1H-1,2,4-Triazol-1-ylmethyl)cycloheptanone
CAS: 313276-51-6
Molecular Formula: C10H15N3O
2-(1H-1,2,4-Triazol-1-ylmethyl)cycloheptanone - Names and Identifiers
| Name | 2-(1H-1,2,4-Triazol-1-ylmethyl)cycloheptanone |
| Synonyms | 2-(1H-1,2,4-Triazol-1-ylmethyl)cycloheptanone |
| CAS | 313276-51-6 |
2-(1H-1,2,4-Triazol-1-ylmethyl)cycloheptanone - Physico-chemical Properties
| Molecular Formula | C10H15N3O |
| Molar Mass | 193.25 |
| Density | 1.25±0.1 g/cm3(Predicted) |
| Melting Point | 80-82 °C |
| Boling Point | 369.6±34.0 °C(Predicted) |
| pKa | 2.73±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD00600399 |
2-(1H-1,2,4-Triazol-1-ylmethyl)cycloheptanone - Introduction
2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone is an organic compound with the chemical formula C10H15N3O. It is a reagent commonly used in organic synthesis.
The following are some properties and applications of 2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone:
Nature:
-Appearance: Colorless to light yellow solid
-Molecular weight: 185.25g/mol
-Melting point: about 65-68°C
-Boiling point: about 340°C
-Solubility: Soluble in polar organic solvents (such as ethanol, dichloromethane and dimethyl amide), insoluble in water.
Use:
- 2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone is an important intermediate for the synthesis of other organic compounds, which can be used for the preparation of drugs, pesticides and dyes.
-It can also be used as a reaction reagent for heterocyclic compounds and participate in various organic synthesis reactions.
Preparation Method:
The preparation method of 2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone usually involves the following steps:
1. First, a cyanoketone compound is prepared by cyanation reaction of phenylpropanal.
2. Next, cyano ketone is reacted with bromo tert-butanol to undergo a ring-closing reaction to obtain the target compound 2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone.
Safety Information:
2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone has limited safety information and should be handled with caution. It can be irritating and damaging to the skin, eyes, and respiratory tract. When in use, appropriate personal protective measures should be taken, such as wearing protective glasses, gloves and respiratory protection. Avoid inhalation, ingestion or contact with skin during operation. Any possible exposure should be cleaned promptly. If discomfort occurs, seek medical attention immediately. Follow the safe handling instructions when using or storing this compound.
The following are some properties and applications of 2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone:
Nature:
-Appearance: Colorless to light yellow solid
-Molecular weight: 185.25g/mol
-Melting point: about 65-68°C
-Boiling point: about 340°C
-Solubility: Soluble in polar organic solvents (such as ethanol, dichloromethane and dimethyl amide), insoluble in water.
Use:
- 2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone is an important intermediate for the synthesis of other organic compounds, which can be used for the preparation of drugs, pesticides and dyes.
-It can also be used as a reaction reagent for heterocyclic compounds and participate in various organic synthesis reactions.
Preparation Method:
The preparation method of 2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone usually involves the following steps:
1. First, a cyanoketone compound is prepared by cyanation reaction of phenylpropanal.
2. Next, cyano ketone is reacted with bromo tert-butanol to undergo a ring-closing reaction to obtain the target compound 2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone.
Safety Information:
2-(1H-1, 2,4-triazol-1-ylmethyl) cycloacetone has limited safety information and should be handled with caution. It can be irritating and damaging to the skin, eyes, and respiratory tract. When in use, appropriate personal protective measures should be taken, such as wearing protective glasses, gloves and respiratory protection. Avoid inhalation, ingestion or contact with skin during operation. Any possible exposure should be cleaned promptly. If discomfort occurs, seek medical attention immediately. Follow the safe handling instructions when using or storing this compound.
Last Update：2024-04-09 21:01:54
