2-(2,4-Difluorophenyl)ethylamine

2-(2,4-Difluorophenyl)ethylamine - Names and Identifiers

Name	Benzeneethanamine, 2,4-difluoro- (9CI)
Synonyms	2,4-Difluoro-benzeneethanamine 2,4-Difluoro-benzeneethanaMine Benzeneethanamine,2,4-difluoro- 2-(2,4-Difluorophenyl)ethylamine Benzeneethanamine, 2,4-difluoro- (9CI)
CAS	134672-72-3

2-(2,4-Difluorophenyl)ethylamine - Physico-chemical Properties

Molecular Formula	C8H9F2N
Molar Mass	157.16
Density	1.169
Boling Point	197℃
Flash Point	87℃
pKa	9.41±0.10(Predicted)
Storage Condition	2-8 ℃, dark

2-(2,4-Difluorophenyl)ethylamine - Risk and Safety

UN IDs	2735
Hazard Class	8
Packing Group	Ⅲ

2-(2,4-Difluorophenyl)ethylamine - Introduction

2,4-difluorophenylethylamine, chemical formula C8H8F2N, is an organic compound. It is a white solid with a pungent odor at room temperature. The following is a description of the nature, use, preparation and safety information of 2,4-difluorophenylethylamine:

Nature:
1. Appearance: white solid.
2. solubility: soluble in organic solvents, such as ethanol, ether and dichloromethane.
3. melting point: about 35-37 ℃.
4. Boiling point: about 180-183 ℃.

Use:
1. as a pesticide intermediate: 2,4-difluorophenethylamine can be used to synthesize a variety of pesticides, such as insecticides, weed agents, etc.
2. As a drug intermediate: It can also be used as an intermediate for synthetic drugs, such as anti-cancer drugs and antidepressants.
3. Laboratory research: It can be used as an important reagent for organic synthesis.

Preparation Method:
2,4-difluorophenethylamine can be prepared by the reaction of phenethylamine with difluorophenylboronic acid under alkali-catalyzed conditions. The specific preparation steps include the condensation reaction of phenethylamine and difluorophenylboronic acid, the reduction of the intermediate and the deprotection of the intermediate.

Safety Information:
1. 2,4-Difluorophenethylamine is irritating and should avoid contact with skin, eyes and respiratory tract. Avoid inhaling dust or solutions.
2. use to wear protective gloves, protective glasses and protective masks.
3. should be away from fire and heat sources, stored in a cool, dry place.
4. in the operation to comply with the safety procedures, and take the necessary ventilation measures.
5. Observe local laws and regulations when using and storing.

Please note that when using or preparing 2,4-difluorophenylethylamine, follow laboratory safety procedures and wear personal protective equipment.

Last Update：2024-04-09 15:17:51