2-(2-fluorophenyl)acetohydrazide
2-(2-Fluorophenyl)acetohydrazide
CAS: 116622-94-7
Molecular Formula: C8H9FN2O
2-(2-fluorophenyl)acetohydrazide - Names and Identifiers
| Name | 2-(2-Fluorophenyl)acetohydrazide |
| Synonyms | 2-(2-fluorophenyl)acetohydrazide 2-(2-Fluorophenyl)acetohydrazide Benzeneacetic acid, 2-fluoro-, hydrazide |
| CAS | 116622-94-7 |
2-(2-fluorophenyl)acetohydrazide - Physico-chemical Properties
| Molecular Formula | C8H9FN2O |
| Molar Mass | 168.17 |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Irritant |
| MDL | MFCD09729319 |
2-(2-fluorophenyl)acetohydrazide - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
2-(2-fluorophenyl)acetohydrazide - Introduction
2-(2-Fluorophenyl)acetohydrazide is an organic compound with the chemical formula C8H8FN3O and the following properties:
1. Appearance: 2-(2-Fluorophenyl)acetohydrazide is a white crystalline powder.
2. solubility: the compound is soluble in organic solvents such as alcohols, ketones and ethers, insoluble in water.
3. Melting Point: The melting point of 2-(2-Fluorophenyl)acetohydrazide is about 110-113°C.
4. Stability: Under conventional storage conditions, it is stable and not easy to decompose.
2-(2-Fluorophenyl)acetohydrazide has certain application value in laboratory and industry, and is often used in the following aspects:
1. Pesticide intermediates: It can be used to synthesize pesticides and related compounds.
2. Drug synthesis intermediate: 2-(2-Fluorophenyl)acetohydrazide can be used as an intermediate for the synthesis of drugs and for the synthesis of biologically active compounds.
2-(2-Fluorophenyl)acetohydrazide has the following two preparation methods:
1. Through the reaction of methyl acetoacetate and p-fluorophenylhydrazine, ethyl 2-(2-fluorophenyl) acetate is first generated, and then hydrolysis reaction is carried out to obtain 2-(2-Fluorophenyl)acetohydrazide.
2. By the reaction of p-fluorobenzoic acid and acetohydrazide, 2-(2-Fluorophenyl)acetohydrazide is produced.
Regarding the safety information of 2-(2-Fluorophenyl)acetohydrazide, due to its certain toxicity, the following matters should be paid attention to when using and handling:
1. Avoid direct contact with skin and eyes to avoid irritation and damage.
2. Use appropriate protective equipment during operation, such as laboratory gloves, protective glasses, etc.
3. Operate in a well-ventilated environment to avoid inhaling its vapor or dust.
4. Avoid contact with oxidants and strong acids during storage to avoid dangerous reactions.
5. Comply with relevant regulations and properly dispose of surplus materials and containers.
When using and handling, it is necessary to follow the chemical's safe handling guidelines or consult professional advice on a case-by-case basis.
1. Appearance: 2-(2-Fluorophenyl)acetohydrazide is a white crystalline powder.
2. solubility: the compound is soluble in organic solvents such as alcohols, ketones and ethers, insoluble in water.
3. Melting Point: The melting point of 2-(2-Fluorophenyl)acetohydrazide is about 110-113°C.
4. Stability: Under conventional storage conditions, it is stable and not easy to decompose.
2-(2-Fluorophenyl)acetohydrazide has certain application value in laboratory and industry, and is often used in the following aspects:
1. Pesticide intermediates: It can be used to synthesize pesticides and related compounds.
2. Drug synthesis intermediate: 2-(2-Fluorophenyl)acetohydrazide can be used as an intermediate for the synthesis of drugs and for the synthesis of biologically active compounds.
2-(2-Fluorophenyl)acetohydrazide has the following two preparation methods:
1. Through the reaction of methyl acetoacetate and p-fluorophenylhydrazine, ethyl 2-(2-fluorophenyl) acetate is first generated, and then hydrolysis reaction is carried out to obtain 2-(2-Fluorophenyl)acetohydrazide.
2. By the reaction of p-fluorobenzoic acid and acetohydrazide, 2-(2-Fluorophenyl)acetohydrazide is produced.
Regarding the safety information of 2-(2-Fluorophenyl)acetohydrazide, due to its certain toxicity, the following matters should be paid attention to when using and handling:
1. Avoid direct contact with skin and eyes to avoid irritation and damage.
2. Use appropriate protective equipment during operation, such as laboratory gloves, protective glasses, etc.
3. Operate in a well-ventilated environment to avoid inhaling its vapor or dust.
4. Avoid contact with oxidants and strong acids during storage to avoid dangerous reactions.
5. Comply with relevant regulations and properly dispose of surplus materials and containers.
When using and handling, it is necessary to follow the chemical's safe handling guidelines or consult professional advice on a case-by-case basis.
Last Update：2024-04-09 21:21:28
