2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-chromen-4-one
Demethylnobiletin
CAS: 2174-59-6
Molecular Formula: C20H20O8
2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-chromen-4-one - Names and Identifiers
2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-chromen-4-one - Physico-chemical Properties
| Molecular Formula | C20H20O8 |
| Molar Mass | 388.37 |
| Density | 1.304±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 145-146℃ |
| Boling Point | 601.4±55.0 °C(Predicted) |
| Solubility | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Appearance | Powder |
| pKa | 6.81±0.40(Predicted) |
| Storage Condition | 2-8°C |
| MDL | MFCD08458849 |
| In vitro study | 5-O-Demethylnobiletin (5-demethylnobiletin) promotes neuritogenesis through the activation of MAPK/ERK-, PKC-, and PKA-dependent signaling pathways. |
2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-chromen-4-one - Reference
| Reference Show more | 1. Zhou Qi, talk about anqun, Yi Xin, etc. Identification of broad-peel orange juice from orange juice based on characteristic components of citrus juice polymethoxyflavone [J]. Food and Fermentation Industry, 2019, 45:227-233. 2. Miao Zhi-Shuo, Zhong Yi-ling, Li Hai-Li, Wu Qian, Yi Ding, Tang Wei-Zhuo. LC-MS analysis and HPLC-DAD determination of seven components in the branches of Gardenia jasminoides [J]. Chinese patent medicine, 2021,43(01):117-123. 3. Guijie Li et al. [IF = 3.701]. "Protective effects of polymethoxyflavone-rich cold-pressed orange peel oil against B- induced photoaging on mouse skin."J Funct Foods. 2020 Apr;67:103834 4. [IF=4.35] Qian Yu et al."Aged Pericarpium Citri Reticulatae 'Chachi' Attenuates Oxidative Damage Induced by tert-Butyl Hydroperoxide (t-BHP) in HepG2 Cells."Foods. 2022 Jan;11(3):273 |
2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-chromen-4-one - Introduction
Demethylnobiletin, also known as demethylcitrus glycoside, is a natural plant compound with the chemical formula C16H20O9 and a molecular weight of 356.33g/mol. The substance is usually present in the form of white crystals or powder.
Demethylnobiletin is an effective natural antioxidant with a variety of biological activities such as antibacterial, anti-inflammatory and anti-tumor. It is often used in the food industry as a food additive, can delay the oxidation process of food, improve the quality of food and preservation effect. In addition, it can also be used in the fields of cosmetics, health products and drugs to exert its antioxidant and anti-inflammatory effects.
There are various methods for preparing Demethylnobiletin, including extraction from citrus fruits, microbial fermentation, etc. Among them, the common preparation method is extracted from Sichuan tangerin Peel.
Regarding the safety information of Demethylnobiletin, there is no clear safety data at present. However, as a natural product, it is generally regarded as a relatively safe compound and is often used in food and cosmetics. However, for people with allergies, caution is still needed when using. In the process of use, the dosage should be strictly controlled and relevant laws and regulations and guidance should be followed.
Demethylnobiletin is an effective natural antioxidant with a variety of biological activities such as antibacterial, anti-inflammatory and anti-tumor. It is often used in the food industry as a food additive, can delay the oxidation process of food, improve the quality of food and preservation effect. In addition, it can also be used in the fields of cosmetics, health products and drugs to exert its antioxidant and anti-inflammatory effects.
There are various methods for preparing Demethylnobiletin, including extraction from citrus fruits, microbial fermentation, etc. Among them, the common preparation method is extracted from Sichuan tangerin Peel.
Regarding the safety information of Demethylnobiletin, there is no clear safety data at present. However, as a natural product, it is generally regarded as a relatively safe compound and is often used in food and cosmetics. However, for people with allergies, caution is still needed when using. In the process of use, the dosage should be strictly controlled and relevant laws and regulations and guidance should be followed.
Last Update：2024-04-09 21:54:55
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Product Name: 2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-chromen-4-one Visit Supplier Webpage Request for quotationCAS: 2174-59-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Demethylnobiletin Visit Supplier Webpage Request for quotationCAS: 2174-59-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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