2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxamide - Names and Identifiers
2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxamide - Physico-chemical Properties
2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxamide - Introduction
2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxamide is a compound whose molecular formula is C12H17N5O2. The following are some properties, uses, preparation and safety information about the compound:
Nature:
-Appearance: Common white solid
-Solubility: Soluble in water, also soluble in some organic solvents
-Melting point: about 180-182°C
-Molecular weight: 271.30g/mol
-Chemical structure: structural units containing piperidine and pyrimidine rings, as well as a hydroxymethyl group and a formamide group
Use:
- 2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxamide are often used as intermediates in organic synthesis, especially in the field of medicine.
-It is a common active pharmaceutical ingredient that can be used in the synthesis of anticancer drugs, antiviral drugs and antibacterial drugs.
-This compound can be used as a precursor of alkaloids and has potential application value.
Preparation Method:
- 2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxamide is prepared by many methods. The common method is through the condensation reaction of piperidine and formaldehyde, and then through the reaction of pyrimidine and dimethyl carbonate.
Safety Information:
-Due to the different characteristics of various compounds, the safe operating procedures of individual materials should be observed when using them.
- 2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxamide may be toxic and irritating to the human body, so it should be used with care.
-During use and storage, the safe operation guidelines for chemicals should be followed, and adverse reactions with other chemical substances should be avoided.
-When it comes to the mass production and use of the substance, a comprehensive toxicity and ecological risk assessment should be carried out.
Last Update：2024-04-09 21:04:16