2-(4-Chlorophenyl)-3-oxopropanenitrile

2-(4-Chlorophenyl)-3-oxopropanenitrile - Names and Identifiers

Name	2-(4-Chlorophenyl)-2-cyanoacetaldehyde
Synonyms	USAF EL-67 2-(4-Chlorophenyl)-2-cyanoacetaldehyde 2-(4-Chlorophenyl)-3-oxopropanenitrile 2-(4-CHLOROPHENYL)-3-OXOPROPANENITRILE 2-(4-CHLOROPHENYL)-2-CYANOACETALDEHYDE 2-(p-Chlorophenyl)-2-formylacetonitrile 2-(p-chlorophenyl)-2-formyl-acetonitril alpha-formyl-p-chlorophenylacetonitrile 2-forMyl-2-(4-chlorophenyl) acetonitrile
CAS	62538-21-0
InChI	InChI=1/C9H6ClNO/c10-9-3-1-7(2-4-9)8(5-11)6-12/h1-4,6,8H

2-(4-Chlorophenyl)-3-oxopropanenitrile - Physico-chemical Properties

Molecular Formula	C9H6ClNO
Molar Mass	179.6
Density	1.263g/cm³
Melting Point	144-146°C
Boling Point	283.8°C at 760 mmHg
Flash Point	125.4°C
Vapor Presure	0.00309mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.552

2-(4-Chlorophenyl)-3-oxopropanenitrile - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3276
Hazard Class	IRRITANT

2-(4-Chlorophenyl)-3-oxopropanenitrile - Introduction

2-(4-Chlorophenyl)-2-cyanoacetaldehyde is an organic compound whose chemical formula is C9H6ClNO. The following is a detailed description of its nature, use, formulation and safety information:

Nature:
-Appearance: 2-(4-Chlorophenyl)-2-cyanoacetaldehyde is a colorless to yellow liquid or solid.
-Solubility: It can be dissolved in organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Melting point: Its melting point range is usually between 50-54 degrees Celsius.
-Stability: 2-(4-Chlorophenyl)-2-cyanoacetaldehyde is stable at room temperature and has good stability to air and light.

Use:
-Intermediate: It is an important intermediate in organic synthesis and can be used to synthesize various heterocyclic compounds, drugs and pesticides.
-ketohydrate reaction: 2-(4-Chlorophenyl)-2-cyanoacetaldehyde can carry out ketohydrate reaction and be used in organic synthesis.
-acetaldehyde reaction: It can also participate in various acetaldehyde reactions, such as nucleophilic addition reactions.

Preparation Method:
-Through oxidation and carbon cyanide reaction: 2-(4-Chlorophenyl)-2-cyanoacetaldehyde can be prepared by reacting p-chlorobenzaldehyde with hydrogen cyanide in the presence of an oxidant.

Safety Information:
-Toxicity: 2-(4-Chlorophenyl)-2-cyanoacetaldehyde is toxic to humans and may cause irritation to the respiratory tract, skin and eyes.
-Combustibility: It is a flammable liquid and should be kept away from open flames and high temperature leads.
-Storage: It should be stored in a cool, dry, ventilated place to avoid contact with oxidants and acids.

Please note that when using or handling any chemical substances, you should follow appropriate safety procedures and consult a professional for more detailed information when necessary.

Last Update：2024-04-09 15:17:58