Molecular Formula | C13H8ClN3O2 |
Molar Mass | 273.67 |
Solubility | ( < 1 mg/ml refers to the product slightly soluble or insoluble) |
Storage Condition | -20℃ |
In vivo study | GABAA receptor agent 1 (30 mg/kg; intraperitoneal) inhibits the maximum electroshock (MES) and pentylenetetrazole (PTZ)-induced convulsions in swiss albino rats. |
Reference Show more | 1. Jain P, et al. Design, synthesis and biological evaluation of some novel benzimidazole derivatives for their potential anticonvulsant activity. Arch Pharm Res. 2010 Jul;33(7):971-80. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.654 ml | 18.27 ml | 36.54 ml |
5 mM | 0.731 ml | 3.654 ml | 7.308 ml |
10 mM | 0.365 ml | 1.827 ml | 3.654 ml |
5 mM | 0.073 ml | 0.365 ml | 0.731 ml |
biological activity | GABAA receptor agent 1 is a high affinity ligand of GABAA receptor, which has strong anticonvulsant activity. |