2-(4-Hydroxy-3-methoxyphenyl)acetonitrile

2-(4-Hydroxy-3-methoxyphenyl)acetonitrile - Names and Identifiers

Name	4-HYDROXY-3-METHOXYPHENYLACETONITRILE
Synonyms	HOMOVANILLONITRILE 4-HYDROXY-3-METHOXYPHENYLACETONITRILE 2-(4-Hydroxy-3-methoxyphenyl)acetonitrile 2-(4-hydroxy-3-methoxy-phenyl)ethanenitrile 3-Methoxy-4-hydroxybenzeneacetonitrileHomovanillonitrile
CAS	4468-59-1
EINECS	224-739-5

2-(4-Hydroxy-3-methoxyphenyl)acetonitrile - Physico-chemical Properties

Molecular Formula	C9H9NO2
Molar Mass	163.17
Density	1.2021 (rough estimate)
Melting Point	56-57 °C (lit.)
Boling Point	135-145 °C/2 mmHg (lit.)
pKa	9.69±0.18(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.5270 (estimate)

2-(4-Hydroxy-3-methoxyphenyl)acetonitrile - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
Hazard Class	IRRITANT-HARMFUL

2-(4-Hydroxy-3-methoxyphenyl)acetonitrile - Upstream Downstream Industry

Raw Materials	(3-Hydroxy-4-methoxy-phenyl)-acetonitrile 2-(Hydroxyimino)-3-(3-methoxy-4-hydroxyphenyl)propionic acid Phenol, 4-[(ethoxymethoxy)methyl]-2-methoxy- Vanillyl alcohol NA TETRABUTYLAMMONIUM CYANIDE POTASSIUM CYANIDE Sodium cyanide sodium:cyanide (3,4-Dimethoxyphenyl)acetonitrile Vanillin
Downstream Products	4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE

2-(4-Hydroxy-3-methoxyphenyl)acetonitrile - Introduction

It is an organic compound with the chemical formula C9H9NO2. Its properties are as follows:

1. Appearance: White to light yellow crystalline solid.

2. Solubility: It is soluble in organic solvents such as Alcohols, Ketones and esters, and rarely soluble in water.

3. Melting Point: the melting point of the IS 118-121 ° C.

4. Uses: It is an important intermediate compound and has a wide range of applications in pharmaceutical synthesis and organic synthesis. It is often used in the preparation of organic compounds such as pharmaceuticals and pesticides.

5. Preparation method: a common preparation method is obtained by the substitution reaction of methyl aminobenzoate, that is, methyl aminobenzoate is reacted with bromoacetonitrile and then dehydroxylated with alkali.

6. Safety information: There is no clear report on the toxicity and danger of the pill. However, as an organic compound, it is generally necessary to avoid contact with skin and eyes, avoid inhaling its dust or gas, and properly store, treat and dispose of waste. During use, be sure to follow the relevant safety procedures and laboratory codes. If any discomfort or accident occurs, please seek medical assistance in a timely manner.

Last Update：2024-04-09 21:21:28