2-(4-Trifluoromethylphenyl)-pyrrolidine

2-(4-Trifluoromethylphenyl)-pyrrolidine - Names and Identifiers

Name	2-(4-Trifluoromethylphenyl)-pyrrolidine
Synonyms	2-(4-Trifluoromethylphenyl)pyrrolidine 2-(4-Trifluoromethylphenyl)Pyrrolidine 2-(4-Trifluoromethylphenyl)-pyrrolidine 2-[4-(Trifluoromethyl)phenyl]pyrrolidine 2-(4-TRIFLUOROMETHYL-PHENYL)-PYRROLIDINE Pyrrolidine, 2-[4-(trifluoromethyl)phenyl]- pyrrolidine, 2-[4-(trifluoromethyl)phenyl]- (2R)-2-[4-(TRIFLUOROMETHYL)PHENYL]PYRROLIDINE-HCL tert-butyl 3-allyl-3-hydroxyazetidine-67-carboxylate
CAS	298690-84-3
InChI	InChI=1/C11H12F3N/c12-11(13,14)9-5-3-8(4-6-9)10-2-1-7-15-10/h3-6,10,15H,1-2,7H2

2-(4-Trifluoromethylphenyl)-pyrrolidine - Physico-chemical Properties

Molecular Formula	C11H12F3N
Molar Mass	215.21
Density	1.179g/cm³
Boling Point	254.1°C at 760 mmHg
Flash Point	107.5°C
Vapor Presure	0.0176mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.473

2-(4-Trifluoromethylphenyl)-pyrrolidine - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note	Irritant

2-(4-Trifluoromethylphenyl)-pyrrolidine - Introduction

2-(4-Trifluoromethylphenyl)-pyrrolidine is an organic compound with the molecular formula C12H12F3N. The following is a description of its nature, use, preparation and safety information:

Nature:
2-(4-Trifluoromethylphenyl)-pyrrolidine is a colorless liquid with a special smell. It has a density of 1.174g/cm³, a boiling point of 170-172°C and a melting point of -34.4°C. It is a flammable liquid, soluble in a variety of organic solvents.

Use:
2-(4-Trifluoromethylphenyl)-pyrrolidine has many applications in the field of chemistry. It can be used as an intermediate and catalyst in organic synthesis reactions. It also has certain applications in drug synthesis, can be used as the basic structural unit of drug molecules, and give drugs certain physical and chemical properties.

Method:
The preparation of 2-(4-Trifluoromethylphenyl)-chrrolidine can be carried out by various methods. One of the commonly used methods is the reaction of 4-trifluoromethylphenylacetonitrile and propylenediamine in an appropriate solvent to obtain the desired product. Specific reaction conditions and catalyst selection can be optimized according to actual needs.

Safety Information:
2-(4-Trifluoromethylphenyl)-pyrrolidine is a chemical, and you need to pay attention to safety when using it. It is irritating and may cause damage to the eyes, skin and respiratory system. Personal protective measures should be taken when touching, such as wearing appropriate glasses, gloves and protective clothing, and ensuring that the operation is carried out in a well-ventilated area. Avoid inhaling its vapors and keep away from sources of ignition. Please observe the appropriate safety procedures during use and storage.

Last Update：2024-04-09 19:05:48