2-(4-aminophenyl)-2-methylpropanenitrile

Name	2-(4-aminophenyl)-2-methylpropanenitrile
Synonyms	2-(4-Aminophenyl)-2-methylpropanonitril 2-(4-Aminophenyl)-2-methylpropionitrile 2-(4-AMINOPHENYL)-2-METHYLPROPANENITRILE 2-(4-aminophenyl)-2-methylpropanenitrile Benzeneacetonitrile, 4-aMino-a,a-diMethyl- Benzeneacetonitrile, 4-amino-α,α-dimethyl- 1,1-dimethyl-1-(4-aminophenyl)-acetonitrile benzeneacetonitrile, 4-amino-alpha,alpha-dimethyl-
CAS	115279-57-7
InChI	InChI=1/C10H12N2/c1-10(2,7-11)8-3-5-9(12)6-4-8/h3-6H,12H2,1-2H3

Molecular Formula	C10H12N2
Molar Mass	160.22
Density	1.055±0.06 g/cm3(Predicted)
Boling Point	173-174 °C(Press: 10 Torr)
Flash Point	142.026°C
Vapor Presure	0.001mmHg at 25°C
pKa	3.63±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive	IRRITANT
Refractive Index	1.556
MDL	MFCD09909912

introduction	2-(4-aminophenyl)-2-methylpropionitrile is both cyanide and aromatic primary amine, so it has multiple reaction sites and is an important pharmaceutical and chemical intermediate.
application	2-(4-aminophenyl)-2-methylpropiononitrile can be used as an intermediate in organic synthesis and a pharmaceutical intermediate, and can be mainly used in laboratory research and development and chemical production.
use	2-(4-aminophenyl)-2-methylpropionitrile is used as an organic and pharmaceutical intermediate.
preparation	2-(4-nitrophenyl)-2-methylpropionitrile is used as the starting material for hydrogenation reduction reaction, Raney nickel is used as the catalyst to prepare 2-(4-aminophenyl)-2-methylpropionitrile, or 2-(4-chlorophenyl)-2-methylpropiononitrile is used as the starting material to prepare 2-(4-aminophenyl)-2-methylpropiononitrile through ammonolysis reaction. The synthesis reaction formula is as follows:

Last Update：2024-04-09 15:16:35