2-(4-aminophenyl)acetamide

2-(4-aminophenyl)acetamide - Names and Identifiers

Name	2-(4-aminophenyl)acetamide
Synonyms	4-AMino-benzeneacetaMide 4-Amino-benzeneacetamide 2-(4-aminophenyl)acetamide BENZENEACETAMIDE, 4-AMINO- Benzeneacetamide, 4-amino- (9CI)
CAS	6633-76-7
InChI	InChI=1/C8H10N2O/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4H,5,9H2,(H2,10,11)

2-(4-aminophenyl)acetamide - Physico-chemical Properties

Molecular Formula	C8H10N2O
Molar Mass	150.18
Density	1.198g/cm³
Boling Point	399.2°C at 760 mmHg
Flash Point	195.2°C
Vapor Presure	1.39E-06mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.612

2-(4-aminophenyl)acetamide - Introduction

2-(4-aminophenyl)acetamide, chemical formula C8H9NO, is a white crystalline powder. It has moderate solubility and is soluble in water and ethanol. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline powder
-Molecular weight: about 151.2g/mol
-Melting point: about 146-152 degrees Celsius
-Boiling point: about 368 degrees Celsius (expected)
-Density: about 1.24g/cm3 (expected)
-Functional group: The compound contains an amino group (-NH2) and an acyl group (-C(O)CH3), which give the compound specific properties and reactivity.

Use:
- 2-(4-aminophenyl)acetamide can be used as a pharmaceutical intermediate for the synthesis of other compounds.
-It is also used as an ingredient in cosmetics and personal care products.
-The compound has antibacterial and anti-inflammatory effects, so it may have certain application potential in the pharmaceutical field or cosmetics.

Preparation Method:
The preparation of 2-(4-aminophenyl)acetamide is usually carried out by the following steps:
1.4-nitrophenol reacts with acetic anhydride to generate 4-acetaminophenol.
2. Reduction of 4-acetaminophenol gives 2-(4-aminophenyl)acetamide.

Safety Information:
- 2-(4-aminophenyl)acetamide has a certain degree of stability under general conditions, but it still needs to be kept away from fire sources and avoid contact with strong oxidants.
-Appropriate personal protective measures, such as wearing gloves and goggles, must be taken when using or handling the compound.
-This compound may cause irritation to the skin, eyes, and respiratory tract. Immediate rinse with water and seek medical help if touched.
-When storing and handling this compound, it is necessary to strictly follow relevant safety procedures to avoid mixing with other chemicals and mishandling.

Last Update：2024-04-09 15:17:59