Molecular Formula | C7H7ClN2O |
Molar Mass | 170.6 |
Density | 1.264±0.06 g/cm3(Predicted) |
Melting Point | 41-43°C |
Boling Point | 317.8±27.0 °C(Predicted) |
Flash Point | 166.914°C |
Solubility | Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met |
Vapor Presure | 0mmHg at 25°C |
Appearance | Light-yellow solid |
Color | Off-White to Light Yellow Low-Melting |
pKa | 13.41±0.46(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.575 |
MDL | MFCD02185921 |
Hazard Symbols | Xn - Harmful |
Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes |
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
introduction | N-methyl -4-chloro -2-picolinamide is a white powdery substance, which is an intermediate of sorafenib, a clinical anticancer drug for the treatment of liver and renal cell carcinoma; Sorafenib intermediate. |
application | N-methyl -4-chloro -2-pyridine formamide can be used as an intermediate in organic synthesis and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical and pharmaceutical synthesis process. |