2-(4-methylsulfonylphenyl)ethanamine
2-[4-(Methylsulfonyl)phenyl]ethylamine
CAS: 153402-45-0
Molecular Formula: C9H13NO2S
2-(4-methylsulfonylphenyl)ethanamine - Names and Identifiers
2-(4-methylsulfonylphenyl)ethanamine - Physico-chemical Properties
| Molecular Formula | C9H13NO2S |
| Molar Mass | 199.27 |
| Density | 1.188±0.06 g/cm3(Predicted) |
| Boling Point | 377.1±34.0 °C(Predicted) |
| pKa | 9.34±0.10(Predicted) |
2-(4-methylsulfonylphenyl)ethanamine - Introduction
2-[4-(Methylsulfonyl)phenyl]ethylamine, also known as 4-methylbenzylsulfamide, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular formula: C9H11NOS
-Molecular weight: 181.26g/mol
-Melting point: 23-25 ℃
-Boiling point: 250 ℃
-Properties: Has a sulfamide functional group and an aromatic amine functional group. It is a volatile liquid, soluble in water and easily soluble in most organic solvents.
Use:
-Chemical synthesis: 2-[4-(Methylsulfonyl)phenyl]ethyl amine can be used as an important raw material in organic synthesis, especially in drug synthesis.
-Drug application: It is used as a precursor of anti-inflammatory, hepatoprotective and anti-tumor drugs in the pharmaceutical field.
-Photocuring agent: 2-[4-(Methylsulfonyl)phenyl]ethyl amine can be used as a Photocuring agent for the curing reaction of photosensitive resins.
Method:
The preparation of 2-[4-(Methylsulfonyl)phenyl]ethylamine is typically obtained by reacting benzylamine with sulfuryl chloride. The specific steps are as follows:
1. At low temperature, slowly add benzylamine to thionyl chloride.
2. Reaction The reaction temperature was gradually raised to room temperature and stirring was continued.
3. After reacting for a period of time at room temperature, the thionyl chloride in the reaction solution is washed with cold water, and impurities are washed away with alcohol.
4. Finally, the target product was obtained by distillation under reduced pressure.
Safety Information:
2-[4-(Methylsulfonyl)phenyl]ethylamine generally has no obvious toxicity under normal use, but as an organic compound, the following matters should be paid attention:
-Avoid contact with skin and eyes. Use protective gloves and goggles if necessary.
-Avoid inhaling its vapors and operate in a well-ventilated environment.
-Store in a sealed, dry and cool place away from sources of fire.
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular formula: C9H11NOS
-Molecular weight: 181.26g/mol
-Melting point: 23-25 ℃
-Boiling point: 250 ℃
-Properties: Has a sulfamide functional group and an aromatic amine functional group. It is a volatile liquid, soluble in water and easily soluble in most organic solvents.
Use:
-Chemical synthesis: 2-[4-(Methylsulfonyl)phenyl]ethyl amine can be used as an important raw material in organic synthesis, especially in drug synthesis.
-Drug application: It is used as a precursor of anti-inflammatory, hepatoprotective and anti-tumor drugs in the pharmaceutical field.
-Photocuring agent: 2-[4-(Methylsulfonyl)phenyl]ethyl amine can be used as a Photocuring agent for the curing reaction of photosensitive resins.
Method:
The preparation of 2-[4-(Methylsulfonyl)phenyl]ethylamine is typically obtained by reacting benzylamine with sulfuryl chloride. The specific steps are as follows:
1. At low temperature, slowly add benzylamine to thionyl chloride.
2. Reaction The reaction temperature was gradually raised to room temperature and stirring was continued.
3. After reacting for a period of time at room temperature, the thionyl chloride in the reaction solution is washed with cold water, and impurities are washed away with alcohol.
4. Finally, the target product was obtained by distillation under reduced pressure.
Safety Information:
2-[4-(Methylsulfonyl)phenyl]ethylamine generally has no obvious toxicity under normal use, but as an organic compound, the following matters should be paid attention:
-Avoid contact with skin and eyes. Use protective gloves and goggles if necessary.
-Avoid inhaling its vapors and operate in a well-ventilated environment.
-Store in a sealed, dry and cool place away from sources of fire.
Last Update：2024-04-09 02:00:42
