2-(4-tert-Butylphenyl)-1H-benzimidazole
ZLN005
CAS: 49671-76-3
Molecular Formula: C17H18N2
2-(4-tert-Butylphenyl)-1H-benzimidazole - Names and Identifiers
2-(4-tert-Butylphenyl)-1H-benzimidazole - Physico-chemical Properties
| Molecular Formula | C17H18N2 |
| Molar Mass | 250.34 |
| Density | 1.102±0.06 g/cm3(Predicted) |
| Melting Point | 257-258℃ |
| Boling Point | 415.3±38.0 °C(Predicted) |
| Solubility | DMSO: soluble10mg/mL, clear |
| Appearance | powder |
| Color | white to beige |
| pKa | 11.52±0.10(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| In vitro study | In L6 myotubes, ZLN005 increases the expression of the PGC-1α gene and downstream genes by activating AMP-activated protein kinases, increasing glucose uptake and fatty acid oxidation, without significant toxicity. In rat primary hepatocytes, ZLN005 did not have the same effect, indicating cell type specificity. In L6 myotubes, ZLN005 increased the expression of PGC-1α and downstream genes by activating AMP-activated protein kinase, increasing glucose uptake and fatty acid oxidation, without significant toxicity. In rat primary hepatocytes, ZLN005 did not have the same effect, indicating cell type specificity. |
| In vivo study | ZLN005(15 mg/kg, P. O.) produced antihyperglycemic and antihyperlipidemic effects while increasing insulin sensitivity in db/db mice and no effect in lean mice. ZLN005(15 mg/kg, P. O.) produced antihyperglycemic and antihyperlipidemic effects while increasing insulin sensitivity in db/db mice and no effect in lean mice. |
2-(4-tert-Butylphenyl)-1H-benzimidazole - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
2-(4-tert-Butylphenyl)-1H-benzimidazole - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.995 ml | 19.973 ml | 39.946 ml |
| 5 mM | 0.799 ml | 3.995 ml | 7.989 ml |
| 10 mM | 0.399 ml | 1.997 ml | 3.995 ml |
| 5 mM | 0.08 ml | 0.399 ml | 0.799 ml |
Last Update：2024-01-02 23:10:35
2-(4-tert-Butylphenyl)-1H-benzimidazole - Introduction
ZLN005 is an organic compound with the chemical formula C18H20N2. It is a white crystalline solid with the characteristic structure of benzimidazole.
ZLN005 is commonly used in catalysts, fluorescent probes and Analytical reagents. It has good catalytic performance and can be used in a variety of organic reactions, such as hydrogenation reaction, olefin cyclization reaction. At the same time, its fluorescent properties make it a potential analytical reagent for detecting metal ions in the environment and molecules in biological samples.
The method for preparing ZLN005 is usually synthesized by reacting benzimidazole and 4-tert-butylbromobenzene. In the specific operation, benzimidazole and 4-tert-butylbromobenzene are first reacted by heating in an organic solvent, and then purified by crystallization or column chromatography to obtain the target product.
Regarding safety information, ZLN005 has low toxicity, but it has an irritating effect on the skin and eyes. During the operation, appropriate protective measures should be worn to avoid direct contact. At the same time, it is also a flammable substance and should be kept away from fire and high temperature.
ZLN005 is commonly used in catalysts, fluorescent probes and Analytical reagents. It has good catalytic performance and can be used in a variety of organic reactions, such as hydrogenation reaction, olefin cyclization reaction. At the same time, its fluorescent properties make it a potential analytical reagent for detecting metal ions in the environment and molecules in biological samples.
The method for preparing ZLN005 is usually synthesized by reacting benzimidazole and 4-tert-butylbromobenzene. In the specific operation, benzimidazole and 4-tert-butylbromobenzene are first reacted by heating in an organic solvent, and then purified by crystallization or column chromatography to obtain the target product.
Regarding safety information, ZLN005 has low toxicity, but it has an irritating effect on the skin and eyes. During the operation, appropriate protective measures should be worn to avoid direct contact. At the same time, it is also a flammable substance and should be kept away from fire and high temperature.
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: ZLN005 Visit Supplier Webpage Request for quotationCAS: 49671-76-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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