2-(5-tributylstannyl-1,3-thiazol-2-yl)propan-2-ol - Names and Identifiers
2-(5-tributylstannyl-1,3-thiazol-2-yl)propan-2-ol - Physico-chemical Properties
Molecular Formula | C18H35NOSSn
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Molar Mass | 432.2516 |
Storage Condition | Room Temprature |
2-(5-tributylstannyl-1,3-thiazol-2-yl)propan-2-ol - Introduction
2-(5-(Tributylstannyl)thiazol-2-yl)propan-2-ol is an organic compound whose chemical formula is C18H33NOSn. The following is an introduction to its properties, uses, preparation methods and safety information:
Properties: 2-(5-(Tributylstannyl)thiazol-2-yl)propan-2-ol is a colorless liquid with a pungent odor. It crystallizes easily at low temperatures and decomposes at high temperatures. It is soluble in organic solvents such as ethanol and ether at normal temperature.
Uses: 2-(5-(Tributylstannyl)thiazol-2-yl)propan-2-ol is commonly used as a reagent in organic synthesis. It can be used to construct new organic molecules, especially for the study of coordination chemistry and organometallic chemistry.
preparation method: 2-(5-(Tributylstannyl)thiazol-2-yl)propan-2-ol can be synthesized by various methods. the following is a common synthesis route: first, disteryl butyl acetate is reacted with N-butyl thiamide by nucleophilic substitution reaction to obtain 2-(5-(butoxy) thiazol-2-yl) butyl acetate. The butyl acetate is then reduced to 2-(5-(butoxy) thiazol-2-yl) acetic acid using a catalytic hydrogenation reaction. Next, the acetic acid functional group is converted to the alkyl tin reagent by a Grignard reaction and appropriate manipulations to produce the 2-(5-(Tributylstannyl)thiazol-2-yl)propan-2-ol.
Safety information: 2-(5-(Tributylstannyl)thiazol-2-yl)propan-2-ol is an organic compound and should be operated in accordance with laboratory safety regulations. It may be irritating to the eyes, skin and respiratory tract. Avoid direct contact and wear appropriate protective equipment, such as glasses, gloves and protective clothing. In case of accidental exposure, immediately flush the affected area with water and seek medical help. In addition, care should be taken to store it in a dry, cool place, away from fire and oxidants.
Last Update:2024-04-10 22:29:15