2-(6-methoxynaphthalen-2-yl)propan-1-ol
Naproxol
CAS: 26159-36-4
Molecular Formula: C14H16O2
2-(6-methoxynaphthalen-2-yl)propan-1-ol - Names and Identifiers
| Name | Naproxol |
| Synonyms | RS-4034 Naproxol (S)-2-(6-Methoxy-2-naphtyl)-1-propanol 2-(6-methoxynaphthalen-2-yl)propan-1-ol 2-(6-Methoxynaphthalen-2-yl)propan-1-ol (-)-2-(6-Methoxy-2-naphthyl)-1-propanol (S)-2-(6-methoxy-naphthalen-2-yl)propan-1-ol (2S)-2-(6-methoxynaphthalen-2-yl)propan-1-ol 6-Methoxy-2-(2-methylhydroxyethyl)naphthalene (-)-6-Methoxy-beta-methyl-2-naphthaleneethanol [S,(-)]-6-Methoxy-β-methyl-2-naphthaleneethanol 2-Naphthaleneethanol, 6-methoxy-β-methyl-, (βS)- |
| CAS | 26159-36-4 |
| InChI | InChI=1/C14H16O2/c1-10(9-15)11-3-4-13-8-14(16-2)6-5-12(13)7-11/h3-8,10,15H,9H2,1-2H3/t10-/m1/s1 |
2-(6-methoxynaphthalen-2-yl)propan-1-ol - Physico-chemical Properties
| Molecular Formula | C14H16O2 |
| Molar Mass | 216.28 |
| Density | 1.108±0.06 g/cm3(Predicted) |
| Melting Point | 87 °C |
| Boling Point | 362.9±17.0 °C(Predicted) |
| Flash Point | 162.6°C |
| Vapor Presure | 6.67E-06mmHg at 25°C |
| pKa | 14.75±0.10(Predicted) |
| Refractive Index | 1.597 |
2-(6-methoxynaphthalen-2-yl)propan-1-ol - Introduction
Naproxol(Naproxol) is a non-steroidal anti-inflammatory drug, which belongs to the class of non-selective cyclooxygenase inhibitors. Its chemical name is (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, its chemical formula is C14H14O3, and its molecular weight is 230.26g/mol.
Naproxol is commonly used to relieve pain, fever and inflammation, particularly in the treatment of conditions such as arthritis, rheumatoid arthritis and dysmenorrhea. It reduces pain and discomfort caused by inflammation by inhibiting the activity of epoxidase in the body.
The preparation method of Naproxol is generally obtained by sulfonation, hydrolysis and acetonitrile acidification of naphthalene. The specific preparation method can be selected according to the method of different research literature.
For safety information, note the following when using Naproxol:
1. Naproxol may cause gastrointestinal discomfort, such as gastric ulcer, indigestion, etc. It is recommended to take it after meals or with food to reduce discomfort.
2. Long-term or excessive use of Naproxol may cause liver damage. During use, please strictly follow the doctor's advice and conduct regular liver function tests.
3. For patients with respiratory diseases such as asthma and allergic rhinitis, Naproxol may cause allergic reactions, such as dyspnea and asthma attack. Special attention should be paid when using.
4. For pregnant and lactating women, the use of Naproxol needs to be carried out under the guidance of a doctor to avoid adverse effects on the fetus or baby.
Naproxol is commonly used to relieve pain, fever and inflammation, particularly in the treatment of conditions such as arthritis, rheumatoid arthritis and dysmenorrhea. It reduces pain and discomfort caused by inflammation by inhibiting the activity of epoxidase in the body.
The preparation method of Naproxol is generally obtained by sulfonation, hydrolysis and acetonitrile acidification of naphthalene. The specific preparation method can be selected according to the method of different research literature.
For safety information, note the following when using Naproxol:
1. Naproxol may cause gastrointestinal discomfort, such as gastric ulcer, indigestion, etc. It is recommended to take it after meals or with food to reduce discomfort.
2. Long-term or excessive use of Naproxol may cause liver damage. During use, please strictly follow the doctor's advice and conduct regular liver function tests.
3. For patients with respiratory diseases such as asthma and allergic rhinitis, Naproxol may cause allergic reactions, such as dyspnea and asthma attack. Special attention should be paid when using.
4. For pregnant and lactating women, the use of Naproxol needs to be carried out under the guidance of a doctor to avoid adverse effects on the fetus or baby.
Last Update：2024-04-10 22:29:15
