2-(Adamantan-1-yl)-N-hydroxyacetamide
2-(1-Adamantyl)-N-Hydroxyacetamide
CAS: 136561-40-5
Molecular Formula: C12H19NO2
2-(Adamantan-1-yl)-N-hydroxyacetamide - Names and Identifiers
| Name | 2-(1-Adamantyl)-N-Hydroxyacetamide |
| Synonyms | 2-(1-Adamantyl)-N-Hydroxyacetamide 2-(AdaMantan-1-yl)-N-hydroxyacetaMide 2-(Adamantan-1-yl)-N-hydroxyacetamide Tricyclo[3.3.1.13,7]decane-1-acetamide, N-hydroxy- N-hydroxy-2-tricyclo[3.3.1.1~3,7~]dec-1-ylacetamide tricyclo[3.3.1.1~3,7~]decane-1-acetamide, N-hydroxy- |
| CAS | 136561-40-5 |
| InChI | InChI=1/C12H19NO2/c14-11(13-15)7-12-4-8-1-9(5-12)3-10(2-8)6-12/h8-10,15H,1-7H2,(H,13,14) |
2-(Adamantan-1-yl)-N-hydroxyacetamide - Physico-chemical Properties
| Molecular Formula | C12H19NO2 |
| Molar Mass | 209.28 |
| Density | 1.194±0.06 g/cm3(Predicted) |
| pKa | 9.48±0.20(Predicted) |
| Refractive Index | 1.559 |
2-(Adamantan-1-yl)-N-hydroxyacetamide - Introduction
2-(1-Adamantane)-N-hydroxyacetamide is an organic compound having an adamantyl group and a hydroxyacetamide group in its structure. Its chemical formula is C10H21NO2.
Nature:
2-(1-Adamantane)-N-hydroxyacetamide is a colorless to pale yellow liquid with a special odor. It is soluble in water and some organic solvents at room temperature.
Use:
2-(1-adamantane)-N-hydroxyacetamide is widely used in chemistry and biochemistry. It can be used as a raw material for the synthesis and modification of compounds, as well as for the preparation of drugs, surfactants and polymers.
Preparation Method:
The synthesis of 2-(1-adamantane)-N-hydroxyacetamide is usually prepared by reacting p-hydroxyacetamide with 1-bromopentane (adamantylating reagent). The reaction is carried out in a suitable solvent and under heating conditions such that the hydrogens of the hydroxyacetamide are replaced by adamantyl groups.
Safety Information:
Exposure of 2-(1-adamantane)-N-hydroxyacetamide may cause irritation and allergic reactions. It is irritating to the eyes and skin and may cause inflammation. Avoid contact with skin and eyes during use, and wear protective gloves and goggles if necessary. During storage and handling, reaction with strong oxidants and strong acids should be avoided to prevent the production of hazardous substances. If exposed or inhaled, seek medical attention immediately. Pay attention to proper laboratory handling and personal protective measures when using or handling the compound.
Nature:
2-(1-Adamantane)-N-hydroxyacetamide is a colorless to pale yellow liquid with a special odor. It is soluble in water and some organic solvents at room temperature.
Use:
2-(1-adamantane)-N-hydroxyacetamide is widely used in chemistry and biochemistry. It can be used as a raw material for the synthesis and modification of compounds, as well as for the preparation of drugs, surfactants and polymers.
Preparation Method:
The synthesis of 2-(1-adamantane)-N-hydroxyacetamide is usually prepared by reacting p-hydroxyacetamide with 1-bromopentane (adamantylating reagent). The reaction is carried out in a suitable solvent and under heating conditions such that the hydrogens of the hydroxyacetamide are replaced by adamantyl groups.
Safety Information:
Exposure of 2-(1-adamantane)-N-hydroxyacetamide may cause irritation and allergic reactions. It is irritating to the eyes and skin and may cause inflammation. Avoid contact with skin and eyes during use, and wear protective gloves and goggles if necessary. During storage and handling, reaction with strong oxidants and strong acids should be avoided to prevent the production of hazardous substances. If exposed or inhaled, seek medical attention immediately. Pay attention to proper laboratory handling and personal protective measures when using or handling the compound.
Last Update：2024-04-09 02:00:42
