2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)-

2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)- - Names and Identifiers

Name	2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE
Synonyms	1-(2,4-difluorophenyl)thiourea 2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)- 2-Aminomethyl-3-chloro-5-(trifluoromethyl)pyridine 3-chloro-2-aminomethyl-5-(trifluoromethyl) pyridine 2-Pyridinemethanamine,3-chloro-5-(trifluoromethyl)- 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine [3-Chloro-5-(trifluoromethyl)-2-pyridyl]methylamine hydrochloride [3-Chloro-5-(trifluoromethyl)pyridin-2-yl]methylamine hydrochloride (3-chloro-5-(trifluoromethyl)pyridin-2-yl)methanamine hydrochloride 2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE [3-Chloro-5-(trifluoromethyl)pyridin-2-yl]methylamine hydrochloride
CAS	175277-74-4
InChI	InChI=1/C7H6ClF3N2/c8-5-1-4(7(9,10)11)3-13-6(5)2-12/h1,3H,2,12H2

2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)- - Physico-chemical Properties

Molecular Formula	C7H6ClF3N2
Molar Mass	210.58
Density	1.421±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	226 °C
Boling Point	212.0±35.0℃ (760 Torr)
Flash Point	82.0±25.9℃
Vapor Presure	0.177mmHg at 25°C
pKa	7.85±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.488

2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)- - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R25 - Toxic if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S39 - Wear eye / face protection.
Hazard Note	Harmful
Hazard Class	IRRITANT

2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)- - Introduction

2-(AMINOMETHYL)-3-chroo-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE is an organic compound with the following properties:

1. Appearance: Colorless crystalline solid.
2. Solubility: Soluble in water and many organic solvents.
3. Melting Point: about 110-115 ° C.
4. Molecular formula: C7H6ClF3N2.HCl.

2-(AMINOMETHYL)-3-chlorophyll -5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE is mainly used in the following aspects:

1. Efficient fungicide: The compound has strong biological bactericidal activity, can be used in agriculture, water treatment and other fields, to prevent the reproduction and growth of microorganisms.
2. Chemical reagents: can be used as intermediates in organic synthesis, participate in a variety of organic synthesis reaction.
3. Surfactant: Due to the particularity of its molecular structure, it can be used as a surfactant to improve the wetting performance of liquids in some applications.

The methods for preparing 2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE mainly include the following methods:

1.3-Chloro -5-(trifluoromethyl)-2-pyridine is reacted with methylamine, and then acid is added to obtain hydrochloride salt.
2. In an appropriate solvent, 3-chloro-5-(trifluoromethyl)-2-pyridine is chlorinated with methylamine, and then purified by crystallization to obtain hydrochloride.

Regarding safety information, 2-(AMINOMETHYL)-3-chlorophyll -5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE has certain toxicity, so the following matters should be paid attention to when using and operating:

1. Avoid direct contact with skin and eyes, and use protective gloves and goggles if necessary.
2. In the operation should take good ventilation measures to avoid inhalation of its vapor and dust.
3. Keep sealed when stored, away from fire and flammable substances.
4. Comply with relevant safety operation procedures and regulations during use and handling.
5. When the symptoms of discomfort after exposure to the compound, should promptly seek medical treatment.

In actual use, it is recommended to refer to relevant safety data sheets and technical literature according to specific needs and experimental conditions to ensure safe operation and use.

Last Update：2024-04-10 22:41:30