2-(Boc-aminomethyl)morpholine

2-(Boc-aminomethyl)morpholine - Names and Identifiers

Name	2-N-BOC-AMINOMETHYLMORPHOLINE
Synonyms	2-(Boc-aminomethyl)morpholine 2-N-BOC-AMINOMETHYLMORPHOLINE ert-Butyl(morpholin-2-ylmethyl)carbamate tert-butyl (morpholin-2-ylmethyl)carbamate tert-butyl N-(morpholin-2-ylmethyl)carbamate Carbamic acid,N-(2-morpholinylmethyl)-, 1,1-dimethylethyl ester
CAS	173341-02-1
InChI	InChI=1/C10H20N2O3/c1-10(2,3)15-9(13)12-7-8-6-11-4-5-14-8/h8,11H,4-7H2,1-3H3,(H,12,13)

2-(Boc-aminomethyl)morpholine - Physico-chemical Properties

Molecular Formula	C10H20N2O3
Molar Mass	216.28
Density	1.032±0.06 g/cm3(Predicted)
Boling Point	334.0±17.0 °C(Predicted)
Flash Point	155.8°C
Vapor Presure	0.000131mmHg at 25°C
pKa	12.22±0.46(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.452

2-(Boc-aminomethyl)morpholine - Risk and Safety

Hazard Class

IRRITANT

2-(Boc-aminomethyl)morpholine - Introduction

It is an organic compound with the chemical formula C11H21NO3. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1. Appearance: It is a white crystal powder.
2. Solubility: It has good solubility in common organic solvents (such as ethyl acetate, dimethyl sulfoxide).
3. Melting Point: about 84-86 degrees Celsius.
4. Stability: for the general conditions of oxygen, light and humidity is relatively stable.

Use:
1. Is a commonly used organic synthesis intermediates. It can be applied to various synthesis reactions, for example as an amino-protecting group to protect an amino group in an amination reaction and then remove the protecting group when necessary.
2. It can also be used to synthesize drugs, pesticides and other organic compounds.

Method:
The method of preparation can generate methylene benzylamine through the reaction of benzylamine, and then use the compound to react with 2-hydroxybutyric acid ethyl ester, and then protect the amino group as N-BOC through the protecting group reaction, it is carried out under appropriate conditions.

Safety Information:
1. Irritating to skin, eyes and mucous membranes, should avoid contact when using.
2. It is necessary to operate in a well-ventilated place and use appropriate personal protective equipment, such as gloves and safety glasses.
3. Avoid dust during operation to prevent inhalation or contact. Try to avoid breathing its gas or vapor.
4. In the storage and handling of the compound, should comply with the relevant safety procedures and national laws and regulations.

Last Update：2024-04-09 02:00:43