2-(Bromomethyl)-1-fluoro-3-nitrobenzene

2-(Bromomethyl)-1-fluoro-3-nitrobenzene - Names and Identifiers

Name	2-(Bromomethyl)-1-fluoro-3-nitrobenzene
Synonyms	2-FLUORO-6-NITROBENZYL BROMIDE 2-Bromomethyl-1-fluoro-3-nitrobenzene 2-(Bromomethyl)-1-fluoro-3-nitrobenzene Benzene, 2-(bromomethyl)-1-fluoro-3-nitro- 2-(Bromomethyl)-1-fluoro-3-nitrobenzene, alpha-Bromo-2-fluoro-6-nitrotoluene
CAS	1958-93-6
EINECS	217-801-8

2-(Bromomethyl)-1-fluoro-3-nitrobenzene - Physico-chemical Properties

Molecular Formula	C7H5BrFNO2
Molar Mass	234.02
Density	1.733±0.06 g/cm3(Predicted)
Melting Point	53-54°C
Boling Point	275.5±25.0 °C(Predicted)
Flash Point	120.4 °C
Water Solubility	Insoluble in water.
BRN	2503670
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Lachrymatory
MDL	MFCD00042918

2-(Bromomethyl)-1-fluoro-3-nitrobenzene - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	3261
Hazard Note	Corrosive/Lachrymatory
Hazard Class	8
Packing Group	II

2-(Bromomethyl)-1-fluoro-3-nitrobenzene - Reference Information

use

2-fluoro-6-nitrobenzyl bromide is a new broad-spectrum fungicide pyraclostrobin, which can be used as an intermediate for laboratory research and development and chemical and pharmaceutical synthesis.

preparation

add 1/3 kettle capacity carbon tetrachloride solvent, measured azobisisobutyronitrile and 48% hydrogen bromide to the reaction kettle, stir and heat with steam; Heating to about 75 ℃, adding metered o-nitrotoluene and 30% hydrogen peroxide at the same time to keep the temperature unchanged and maintain the reflux state, the dripping time is about 3-4 hours; after the dripping is over, continue to heat preservation and reflux reaction for 1-2 hours, turn off the steam, cool the temperature to normal temperature, and sample and analyze the content of o-nitrobenzyl bromide: liquid separation, the organic layer adopts 20% NaHSO3 After washing three times of aqueous solution and water, it is distilled at normal pressure to remove the carbon tetrachloride solvent; the reaction liquid is recrystallized with petroleum ether, the crystals are centrifuged, and the crystals are rinsed with cold petroleum ether, white o-nitro benzyl bromide solid products.

Last Update：2024-04-09 20:48:19