2-(Cyclopropyl)pyrimidine-5-boronicacidpinacolester

2-(Cyclopropyl)pyrimidine-5-boronicacidpinacolester - Names and Identifiers

Name	2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine
Synonyms	2-Cyclopropylpyrimidin-5-ylboronicacidpinacolester 2-(Cyclopropyl)pyrimidine-5-boronicacidpinacolester 2-Cyclopropylpyrimidin-5-ylboronic acid pinacol ester 2-(Cyclopropyl)pyrimidine-5-boronic acid pinacol ester 2-cyclopropyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine 2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine Pyrimidine,2-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- Pyrimidine, 2-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CAS	1375301-91-9

2-(Cyclopropyl)pyrimidine-5-boronicacidpinacolester - Physico-chemical Properties

Molecular Formula	C13H19BN2O2
Molar Mass	246.11
Density	1.11±0.1 g/cm3(Predicted)
Boling Point	355.5±15.0 °C(Predicted)
pKa	1.83±0.22(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

2-(Cyclopropyl)pyrimidine-5-boronicacidpinacolester - Introduction

2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine is an organic compound with the chemical formula C14H19BN2O2.

Nature:
1. Appearance: 2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine is a colorless to pale yellow solid.
2. Melting point: about 100-105°C.
3. Solubility: Soluble in common organic solvents.

Use:
2-cyclopyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine is often used as a ligand in organic synthesis, forming complexes with metals and participating in catalytic reactions. It is also widely used in the field of medicinal chemistry as an intermediate in the synthesis of drugs.

Preparation Method:
The preparation of 2-cyclopyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine is generally achieved by a multi-step reaction. A common preparation method is the reaction of 2-bromopropylpyrimidine with 4,4, 5,5-tetramethyl -1,3, 2-dioxaborolane under basic conditions to give the desired product.

Safety Information:
Due to the lack of specific safety information, the use and operation of 2-cyclopylyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine should follow general laboratory safety practices and wear appropriate personal protective equipment. It should be noted that this compound may be harmful to the environment and should be avoided from entering water and soil.

Last Update：2024-04-09 19:05:53