2-(Methylthio)pyrimidine-5-carbonitrile

2-(Methylthio)pyrimidine-5-carbonitrile - Names and Identifiers

Name	2-(Methylthio)pyrimidine-5-carbonitrile
Synonyms	5-Cyano-2-MethylthiopyriMidine 2-(Methylthio)pyridine-5-carbonitrile 2-(Methylthio)pyrimidine-5-carbonitrile 5-Carbonitrile-2-(Methylthio)pyriMidine 5-carbonitrile-2-(methylthio)pyrimidine 2-(methylthio)-5-Pyrimidinecarbonitrile 2-Methylsulfanylpyrimidine-5-carbonitrile 2-METHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE 2-(Methylthio)pyrimidine-5-carbonitrile2-(Methylthio)pyrimidine-5-carbonitrile
CAS	38275-43-3
InChI	InChI=1/C6H5N3S/c1-10-6-8-3-5(2-7)4-9-6/h3-4H,1H3

2-(Methylthio)pyrimidine-5-carbonitrile - Physico-chemical Properties

Molecular Formula	C6H5N3S
Molar Mass	151.19
Density	1.302g/cm³
Boling Point	311.355°C at 760 mmHg
Flash Point	142.103°C
Vapor Presure	0.001mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.597

2-(Methylthio)pyrimidine-5-carbonitrile - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
HS Code	29333990

2-(Methylthio)pyrimidine-5-carbonitrile - Introduction

2-(Methylthio)pyrimidine-5-carbonitrile is an organic compound with the chemical formula C6H5N3S. It is a white crystalline solid, soluble in some organic solvents such as ethanol and dimethylformamide.

2-(Methylthio)pyrimidine-5-carbonitrile has some applications in the field of medicinal chemistry. It can be used as an intermediate for the synthesis of fluorescent dyes and bioactive molecules, and also as a building block for drug molecules. Other applications include as pesticides and dye intermediates.

There are two main methods of preparing 2-(Methylthio)pyrimidine-5-carbonitrile. One is the reaction of 2-methylthiopyrimidine with bromoacetonitrile to give the corresponding nitrile compound. The other is the reaction of 2-methylthiopyrimidine with sodium trichlorocyanide, and further reaction with a methylating reagent to obtain the target product.

Regarding safety information, 2-(Methylthio)pyrimidine-5-carbonitrile may pose a health hazard in contact with skin, inhalation or ingestion. Therefore, protective gloves, protective glasses and protective masks should be worn when in use. At the same time should be away from fire and high temperature environment. Strict chemical safety regulations should be observed during storage and handling to avoid contact with oxidizing agents and strong acids. In case of accidental contact, rinse immediately with plenty of water and seek medical attention immediately.

Last Update：2024-04-09 20:49:11