2-(N-Boc-piperidin-4-yl)bromobenzene

2-(N-Boc-piperidin-4-yl)bromobenzene - Names and Identifiers

Name	N-Boc-4-(2-bromophenyl)piperidine
Synonyms	N-Boc-4-(2-bromophenyl)piperidine 1-Boc-4-(2-bromophenyl)piperidine N-Boc-4-(2-broMophenyl)piperidine 2-(N-Boc-piperidin-4-yl)bromobenzene tert-butyl 4-(2-bromophenyl)piperidine-1-carboxylate 1-Piperidinecarboxylic acid, 4-(2-bromophenyl)-, 1,1-dimethylethyl ester
CAS	1198283-93-0

2-(N-Boc-piperidin-4-yl)bromobenzene - Physico-chemical Properties

Molecular Formula	C16H22BrNO2
Molar Mass	340.26
Storage Condition	Room Temprature

2-(N-Boc-piperidin-4-yl)bromobenzene - Introduction

N-Boc-4-(2-Bromophenyl) piperidine is an organic compound with the following properties:

1. Appearance: colorless or yellowish crystal.
2. melting point: about 100-102 degrees Celsius.
3. solubility: soluble in common organic solvents, such as ethanol and dichloromethane.
4. chemical properties: N-Boc-4-(2-bromophenyl) piperidine is a kind of amide protecting group compound, with the stability of electrophilic reagents.
5. use precautions: should be stored in a cool, dry place, avoid contact with strong oxidants.

The main use of N-Boc-4-(2-bromophenyl) piperidine is as a reagent or intermediate in organic synthesis. It can be used to prepare a variety of organic compounds, such as drugs, peptides and natural products. Its main uses are as follows:

1. drug research: N-Boc-4-(2-bromophenyl) piperidine can be used as a protective group in the synthesis of drugs, intermediates or precursors for the synthesis of drugs.
2. Chemical synthesis: It can be used as an electrophilic reagent in organic synthesis and participate in a variety of chemical reactions, such as substitution reactions, coupling reactions and cyclization reactions.
3. peptide synthesis: N-Boc-4-(2-bromophenyl) piperidine can be used for protecting group strategy in peptide chemistry, and participate in the process of synthesis of complex polypeptides.

The method for preparing N-Boc-4-(2-bromophenyl) piperidine can be carried out by the following steps:

1. First, 4-(2-bromophenyl) piperidine is reacted with an N-tert-butoxycarbonylating agent (such as N-tert-butoxycarbonyl chloride) to obtain N-Boc-4-(2-bromophenyl) piperidine.

Safety Information: The following safety precautions should be taken when using N-Boc-4-(2-bromophenyl) piperidine:

1. Avoid direct contact with skin and eyes. If the external contact touches the skin, rinse immediately with plenty of water and seek medical help.
2. Good ventilation measures should be taken during operation to prevent poisoning or discomfort caused by inhalation or swallowing.
3. Use should wear appropriate personal protective equipment, such as chemical protective gloves and safety glasses.
4. It should be stored away from fire and oxidant to avoid fire and explosion hazards.

Last Update：2024-04-10 22:41:56