2-(Pyrazol-1-yl)pyridine - Names and Identifiers
2-(Pyrazol-1-yl)pyridine - Physico-chemical Properties
Molecular Formula | C8H7N3
|
Molar Mass | 145.16 |
Density | 1.16±0.1 g/cm3(Predicted) |
Melting Point | 37.0 to 41.0 °C |
Boling Point | 265.6±13.0 °C(Predicted) |
pKa | 2.83±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
2-(Pyrazol-1-yl)pyridine - Introduction
Pyridine, 2-(1H-pyrazol-1-yl)-is an organic compound with the formula C11H8N4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Pyridine, 2-(1H-pyrazol-1-yl)-is a solid, usually yellow or orange-yellow crystals.
-Solubility: It has good solubility in common organic solvents.
-Melting point: Its melting point is 100-103 degrees Celsius.
-Spectral data: experimental data such as nuclear magnetic resonance and infrared spectra of Pyridine, 2-(1H-pyrazol-1-yl)-are available for reference.
Use:
- Pyridine, 2-(1H-pyrazol-1-yl)-is commonly used as a reagent and catalyst in organic synthesis.
-It is widely used in the field of medicine, especially as a precursor compound of anti-tumor and anti-inflammatory drugs.
-The compound can also be used to synthesize heterocyclic compounds with biological activity.
Method:
- Pyridine, a common synthesis method of 2-(1H-pyrazol-1-yl)-is to generate 2-bromo-1-yl Pyridine by reacting 1-aminopyrazole with bromoacetate, it is further reacted with tert-butyric acid ester by heating to obtain the target product.
Safety Information:
- Pyridine, 2-(1H-pyrazol-1-yl)-is generally considered relatively safe when used with caution.
-During handling and storage, regular laboratory safety regulations should be followed, such as wearing protective gloves, eye protection and gas masks.
-Due to the lack of sufficient data, its long-term impact on the environment and human body is not clear, so it is necessary to follow the principle of careful use.
Last Update:2024-04-09 21:04:16