2-(Trifluoromethoxy)fluorobenzene
2-(trifluoromethoxy)fluorobenzene
CAS: 2106-18-5
Molecular Formula: C7H4F4O
2-(Trifluoromethoxy)fluorobenzene - Names and Identifiers
2-(Trifluoromethoxy)fluorobenzene - Physico-chemical Properties
| Molecular Formula | C7H4F4O |
| Molar Mass | 180.1 |
| Density | 1.326g/mLat 25°C(lit.) |
| Boling Point | 90°C20mm Hg(lit.) |
| Flash Point | 198°F |
| Vapor Presure | 24.3mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.468(lit.) |
2-(Trifluoromethoxy)fluorobenzene - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R11 - Highly Flammable R36/38 - Irritating to eyes and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S16 - Keep away from sources of ignition. S36 - Wear suitable protective clothing. S33 - Take precautionary measures against static discharges. S28 - After contact with skin, wash immediately with plenty of soap-suds. S15 - Keep away from heat. S7 - Keep container tightly closed. |
| UN IDs | 1993 |
| WGK Germany | 3 |
| HS Code | 29093090 |
| Hazard Note | Irritant |
| Hazard Class | 3 |
| Packing Group | II |
2-(Trifluoromethoxy)fluorobenzene - Introduction
2-(trifluoromethoxy)fluorobenzene(2-(trifluoromethoxy)fluorobenzene) is an organic compound with the chemical formula C7H4F4O. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2-(trifluoromethoxy)fluorobenzene is a colorless liquid.
-Solubility: It can be dissolved in organic solvents, such as ether, chlorinated hydrocarbons.
-Melting point and boiling point: The melting point is -30 ° C, and the boiling point is 50-51 ° C.
-Density: The density of the compound is about 1.48g/cm³.
-Hazard: 2-(trifluoromethoxy)fluorobenzene is a flammable liquid that may cause a fire when exposed to open flames or high temperatures.
Use:
-Pharmaceutical Chemistry: 2-(trifluoromethoxy)fluorobenzene can be used as an important intermediate for the preparation of drugs, pesticides and other organic compounds.
-Synthesis of heterocyclic compounds: It can be used to synthesize various heterocyclic compounds, such as hydrogen-containing heterocycles, nitrogen-containing heterocycles, etc.
Method:
2-(trifluoromethoxy)fluorobenzene is often prepared by reacting aryne and fluorinating agent, and the specific steps are as follows:
1. The arylalkyne is reacted with a fluorinating agent. Common fluorinating agents are ammonium hydrogen borate (NH4HF2) and metal fluorides.
2. The intermediate generated by the reaction reacts with methanol to obtain 2-(trifluoromethoxy)fluorobenzene.
Safety Information:
-When using and storing 2-(trifluoromethoxy)fluorobenzene, strictly follow the safety procedures and avoid contact with skin, eyes and inhalation of its vapors.
-This compound is flammable and should be kept away from fire and hot spots.
-Wear protective gloves, goggles and protective clothing to ensure good ventilation when handling the compound.
Please note that 2-(trifluoromethoxy)fluorobenzene is a chemical substance, and safety procedures should be followed during operation to avoid accidents and injuries.
Nature:
-Appearance: 2-(trifluoromethoxy)fluorobenzene is a colorless liquid.
-Solubility: It can be dissolved in organic solvents, such as ether, chlorinated hydrocarbons.
-Melting point and boiling point: The melting point is -30 ° C, and the boiling point is 50-51 ° C.
-Density: The density of the compound is about 1.48g/cm³.
-Hazard: 2-(trifluoromethoxy)fluorobenzene is a flammable liquid that may cause a fire when exposed to open flames or high temperatures.
Use:
-Pharmaceutical Chemistry: 2-(trifluoromethoxy)fluorobenzene can be used as an important intermediate for the preparation of drugs, pesticides and other organic compounds.
-Synthesis of heterocyclic compounds: It can be used to synthesize various heterocyclic compounds, such as hydrogen-containing heterocycles, nitrogen-containing heterocycles, etc.
Method:
2-(trifluoromethoxy)fluorobenzene is often prepared by reacting aryne and fluorinating agent, and the specific steps are as follows:
1. The arylalkyne is reacted with a fluorinating agent. Common fluorinating agents are ammonium hydrogen borate (NH4HF2) and metal fluorides.
2. The intermediate generated by the reaction reacts with methanol to obtain 2-(trifluoromethoxy)fluorobenzene.
Safety Information:
-When using and storing 2-(trifluoromethoxy)fluorobenzene, strictly follow the safety procedures and avoid contact with skin, eyes and inhalation of its vapors.
-This compound is flammable and should be kept away from fire and hot spots.
-Wear protective gloves, goggles and protective clothing to ensure good ventilation when handling the compound.
Please note that 2-(trifluoromethoxy)fluorobenzene is a chemical substance, and safety procedures should be followed during operation to avoid accidents and injuries.
Last Update：2024-04-09 15:17:55
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Email: r@reformchem.com
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QQ: 3787852685
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Product Name: 2-(trifluoromethoxy)fluorobenzene Request for quotationCAS: 2106-18-5
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Mobile: +86-17551318830
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