2-(Trifluoromethyl)-4-pyrimidinamine

2-(Trifluoromethyl)-4-pyrimidinamine - Names and Identifiers

Name	2-Trifluoromethyl-4-aminopyrimidine
Synonyms	2-Trifluoromethyl-4-aminopyrimidine 2-(Trifluoromethyl)-4-pyrimidinamine 2-(trifluoromethyl)pyrimidin-4-amine 2-Trifluoromethylpyrimidin-4-ylamine 2-(TRIFLUOROMETHYL)PYRIMIDIN-4-AMINE 2-Trifluoromethylpyrimidin-4-ylamine 4-Pyrimidinamine, 2-(trifluoromethyl)-
CAS	672-42-4
InChI	InChI=1/C5H4F3N3/c6-5(7,8)4-10-2-1-3(9)11-4/h1-2H,(H2,9,10,11)

2-(Trifluoromethyl)-4-pyrimidinamine - Physico-chemical Properties

Molecular Formula	C5H4F3N3
Molar Mass	163.1
Density	1.460±0.06 g/cm3(Predicted)
Boling Point	155.3±40.0 °C(Predicted)
Flash Point	47.7°C
Vapor Presure	3.05mmHg at 25°C
pKa	1.53±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.478

2-(Trifluoromethyl)-4-pyrimidinamine - Risk and Safety

Risk Codes	20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S36/37 - Wear suitable protective clothing and gloves. S24/25 - Avoid contact with skin and eyes.
HS Code	29335990

2-(Trifluoromethyl)-4-pyrimidinamine - Introduction

It is an organic compound with a chemical formula of C5H3F3N4 and a molecular weight of 162.10. It is a white crystalline solid, soluble in some organic solvents, such as chloroform and dichloromethane.

It has a wide range of applications in pharmaceutical chemistry and organic synthesis. It can be used as an intermediate in the synthesis of other compounds, for example, for the synthesis of new drugs, chemical raw materials or pesticides. It is also used as a catalyst and ligand.

There are a variety of methods for preparing the pill. One common method is to react 2-trifluoromethyl-4-aminobenzoic acid with cyanogen gas, followed by reduction to give the desired product. Another method is to react 2-trifluoromethyl-4-chloropyrimidine with aminobenzoate.

Regarding safety information, is a chemical that needs to be operated under appropriate laboratory conditions. It can be irritating to the eyes and skin, so avoid contact with skin and eyes and take appropriate safety measures, such as wearing protective gloves and glasses. When storing and handling chemicals, it is necessary to follow safe operating practices. If ingested or inhaled, seek medical attention immediately.

Last Update：2024-04-09 20:44:15